Onemorestep Posted May 31, 2017 Report Share Posted May 31, 2017 Hey guys-- thought some of you might be interested in looking at a fellow travelers gene mutations. The reason I'm posting this in Medication and Other Treatments is that this site, NutraHacker, offers suggestions for supplements and medications to support and avoid in aiding ones bodily functions in light of mutations. https://s3-us-west-2.amazonaws.com/reports.nutrahacker.com/mutationReports/NutraHacker_Complete_Mutation_Report_Customer_028a23b7-9f46-4616-8b5a-39aa49a6e692.pdf Anyone who has had experience with any of these supplements/drugs and wants to share it would be most appreciated. Or if you have any knowledge about the genes themselves feel free to speak up. I know about some like COMT and MTHFR but others are out of my paygrade. For instance, I just learned that selenium is great for the thyroid but if youre deficient in iodine it will make things worse. So interactions etc please let me know XD I listed the supplements below that im supposed to take and avoid. There is some crossover and Im supposedly meant to prioritize based off of my own personal experiences with the conflicting ones. Hope you guys find this as interesting as I do! Ive already started taking Hydroxy B12 and it definitely helps. Encourage: Zinc Whey Vitamin K Vitamin E in tocotrienol form Vitamin D3 Vitamin C Vitamin B6 Vitamin B3 Vitamin B12 Vitamin A TMG Theanine Taurine Sulforaphane Selenium SAMe inhibits Sage Rosemary Rooibos Riboflavin for high blood pressure Ribo-5-phosphate Reduced forms of folate Progesterone Potassium Possibly ketogenic diet Phosphatidylserine Phosphatidylcholine Ornithine/Arginine Ornithine Omega-3 fatty acids like fish oil NAC MSM Molybdenum Methyl B12 Manganese Low fat diet Lithium orotate L-methylfolate Iodine Hydroxy B12 (hydroxycobalamin) Grapeseed extract Glycine Glucarate Fiber Fat soluble antioxidants Diindolylmethane Curcumin CoQ10 Choline Cardamom Beta-alanine Avoid: Vitamin E Vitamin B6 (P-5-P form ok) Taurine Sulfates Noise (greater chance for hearing loss) Nicotine MSG Methyl donors Methyl B12 High fat diet Green tea Grapefruit Folinic acid Folate Estrogens EGCG Curcumin Cumin Cannabis BCAA Androgens Much love, OMS Link to comment Share on other sites More sharing options...
Guest Posted May 31, 2017 Report Share Posted May 31, 2017 How are you going to take these? Are you just going to keep adding more until you're taking all the ones you're supposed to? Link to comment Share on other sites More sharing options...
Onemorestep Posted June 1, 2017 Author Report Share Posted June 1, 2017 I'm going to add them slowly one by one I guess :x pretty anxious about it. I have bad reactions to stuff sometimes so not looking forward to finding out which does. Link to comment Share on other sites More sharing options...
K.B.Fante Posted June 1, 2017 Report Share Posted June 1, 2017 Where did you come up with this? It's hard to see why you'd avoid fat given the brain is largely composed of it and needs it to run. Ever since including more healthy fats in my diet I've felt much better. Also, why no turmeric or taurine? These are both great for HPPD as far as I've heard and experienced. That said, you have these on both lists so I can't read too much into it I guess. The last thing you should do is take tons of supplements. Not a good idea whatsoever. Just start eating super healthy. You can get all of these vitamins and minerals in a healthy, complex diet of mostly veggies and fruits. Link to comment Share on other sites More sharing options...
Onemorestep Posted June 1, 2017 Author Report Share Posted June 1, 2017 I think I'll try a few. I'm mostly concerned with my antioxidant capabilities being impaired and high levels of ammonia. And superoxides. I do wish they had a section for WHY they think these are good supplements though. I should eat healthier. I'm on a keto diet and it treats me well so I eat a lot of salad but sometimes I fall into just eating too much sausages and cheese ;p Link to comment Share on other sites More sharing options...
Onemorestep Posted June 1, 2017 Author Report Share Posted June 1, 2017 Also since taking keppra my hair has been falling out and I would like to figure out why... I'm hoping folate zinc selenium and molybdenum willl help. Link to comment Share on other sites More sharing options...
K.B.Fante Posted June 2, 2017 Report Share Posted June 2, 2017 21 hours ago, Onemorestep said: Also since taking keppra my hair has been falling out and I would like to figure out why... I'm hoping folate zinc selenium and molybdenum willl help. Honestly, the only supplement I think people almost have to have is magnesium just because of our agricultural processes, but as long as you eat a healthy and colorful diet with lots of greens, veggies, fruits, fish, nuts, etc., then you'll get all you need through those foods. Trust me man, I've been down the road of popping all sorts of supplements at one time and it's not an enjoyable experience. They can often make your symptoms worse or just mess with your health in general. Eating healthy is by far the best way to get whatever your brain needs. If you're really set on taking vitamins the only others I'd recommend are lecithin for nervous system support and potential neuronal growth, B complex, fish oil high in DHA and vitamin D. But again, you can get those by eating greens, eating fish and getting sun, which are all part of a healthy lifestyle anyways. Link to comment Share on other sites More sharing options...
Onemorestep Posted June 4, 2017 Author Report Share Posted June 4, 2017 I just started taking some krill oil and I went to the beach today for some good old vitamin D you know interestingly enough I've been craving fish a lot recently. Odd because I've always disliked fish! Also in terms of the hair loss... it actually might be gabapentin causing it. I've been off keppra for months now and the loss has only gotten worse so I googled a bit and there seems to be quite. A few people saying they're having hair issues on gabapentin. But you know it's the internet so who knows. Link to comment Share on other sites More sharing options...
Onemorestep Posted June 8, 2017 Author Report Share Posted June 8, 2017 (edited) So still doing well on a few of these guys. 25 mg b6 P-5-P form 2000 mcg hydroxo b12 10,000 mcg biotin 500mg vitamin C 600 mg NAC 3x daily some over the counter GABA (unsure if this does anything tbh) optimal liposomal glutathione (400mg phosphatydilcholine, glutathione) 30 mcg methylfolate (working my way up very slowly on this to prevent inflammation) After researching Gabapentin I came across some information that it can reduce levels of folate which would put stress on the methylation cycle. I already have many folate methylation gene mutations. https://www.ncbi.nlm.nih.gov/m/pubmed/21246600/ http://www.uofmhealth.org/health-library/hn-1390003 interestingly enough about 2 days ago I experienced a SIGNIFICANT reduction in the pain I've been experiencing from Peyronie's disease. Whether this is from coming off the gabapentin and benzos or because I'm replenishing my b levels and stabilizing the methylation process I do not know. Or perhaps the increased glutathion is aiding in inflammation reduction. Regardless I'm happy with the results. i recommend anyone who is taking anticonvulsants (this includes benzos) to get their biotin, calcium, b12, b6, and folate levels checked. edit:2021 i did not have peyronies disease. I believe it was a collagen issue cause by (theoretical) poor copper utilization. Keppra did cause this issue to be substantially worse (it interacts with a lot of vitamins involving the methylation cycle). I do not use these types of vitamins anymore Edited January 19, 2021 by Onemorestep Link to comment Share on other sites More sharing options...
Onemorestep Posted June 12, 2017 Author Report Share Posted June 12, 2017 I'm finding that the more I withdraw from these downers the more these vitamins make the panic worse. Discontinued today and feel a lot better. Once I've stabilized I'll re enstate them and see how I do. B vitamins are just a bit too stimulating right now! Link to comment Share on other sites More sharing options...
brendan Posted April 20, 2018 Report Share Posted April 20, 2018 does liposomal glutathione do anything beyond what nac will do? Link to comment Share on other sites More sharing options...
Onemorestep Posted May 7, 2018 Author Report Share Posted May 7, 2018 (edited) @brendan i dont think it makes makes a difference in terms of the end result. However NAC comes with other effects that some people might want to avoid. When I tried taking NAC, it made my panic horrific. But then again I tend to react poorly to things that increase ampa. For others this might be preferable and they get benefits from all the moa’s Of NAC edit 2021: NAC can (not directly) bind to methyl-b12 and render it useless. It was screwing up my already screwed up methylation. Edited January 19, 2021 by Onemorestep Link to comment Share on other sites More sharing options...
Bensmith Posted January 18, 2021 Report Share Posted January 18, 2021 So mythl b12 good or bad? Listed both. Also mythl donors are bad? Link to comment Share on other sites More sharing options...
Onemorestep Posted January 19, 2021 Author Report Share Posted January 19, 2021 I consider this post to be very outdated now, both by my reactions to things and also just the website I was using wasn’t great. I now use self decode for my genetics. most importantly, for my methylation I now follow This protocol by Freddd... it is not for the lighthearted and I haven’t made it fully through it but still I have had enormous benefit from it. https://docs.google.com/viewer?a=v&pid=sites&srcid=ZGVmYXVsdGRvbWFpbnx1bHRyYXdlbGxuZXNzcHJvamVjdHxneDo3ODUwNWMwODUyODZjMmM0 Link to comment Share on other sites More sharing options...
rlopes Posted June 10, 2021 Report Share Posted June 10, 2021 Hello! Any updates on this? Did you find a regimen that works? Link to comment Share on other sites More sharing options...
Onemorestep Posted June 13, 2021 Author Report Share Posted June 13, 2021 I found freddds protocol to work for me for quite some time. That is until I got the covid shot. Now my nutritional needs have shifted quite a large bit. Very strange. Link to comment Share on other sites More sharing options...
rlopes Posted June 13, 2021 Report Share Posted June 13, 2021 9 minutes ago, Onemorestep said: I found freddds protocol to work for me for quite some time. That is until I got the covid shot. Now my nutritional needs have shifted quite a large bit. Very strange. Oh man this covid vaccine is scary. Is your HPPD under control at least? Link to comment Share on other sites More sharing options...
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