Nsi-189

[Onemorestep]

This is a compound I haven’t seen a whole lot about on this forum. Years ago, I read pretty much the entire longecity thread about it and was surprised more of us didn’t try it as it appears to promote healing in the hippocampus at least. 

 

I probably would have tried it back then had I been able to find an easy and reputable source. The patent holder was really shutting things down.

 

and then, very much by accident, I stumbled across it on the irc.bio website and immediately ordered both the sulfate and freebase. It was kind of an impulse decision, as I’m not even sure I’m going to take it. I just couldn’t help myself as I’m kind of a collector of strange supplements and medications at this point. 

 

Anyway, if anyone is interested in trying it, it’s there for the taking. Pretty sure irc Bio is closing it’s doors soon though due to increased laws about SARMs and that’s 75 percent of their business.

[Onemorestep]

I also want to state this is a pretty high risk compound in my opinion, As with anything that permanently changes the structure or function of the brain.

 

but... it is FASCINATING. I mean dig around a bit on the internet. The user reports are about as novel as I’ve ever seen. For gods sake one Australian man actually became a genius from using NSI-189. His memory recall is at levels that actually scare me—he says he can tell you what he had for lunch everyday for the last two weeks. 

 

While this is out there, and available, MoA is speculation at best. Cant forget this....

 

really this compound just just makes me really interested for what the future of pharmacology and brain science holds. 

[Joseph C.]

Le vont ah ii crie nord ca rues paix cree?

Edited April 23, 2022 by Joseph C.

[Onemorestep]

I think the person who gave him the nsi said the effect was dose dependent so I assume he has to take it to continue that effect. 

[Onemorestep]

I’m about three weeks into my trial with NSI. In my opinion, it is an INCREDIBLE substance for alleviating depression and promoting mental stability. I feel a sense of security and self that I had lost for so long I had forgotten what it was like. And the effects appear to not only last with cessation of it but actually get better in my experience. 

 

Its still early in my trial to be tooting success, but I’m just in such a state of relief I felt the need to say something. So far this has changed my life so much for the better.

 

Obviously, individual mileage may vary. This is not a zero risk substance. But from what I’ve read and experienced, it’s not more dangerous than traditional antidepressants in terms of side effects.

 

ill continue to post about my experience with this compound as time goes on. I’m still tinkering with dosages and want to give it a full rub before I report back.

 

Much love to you all   

[Onemorestep]

Unfortunately, after a few weeks on nsi it began to cause anxiety. I still take it every 4th day, but at about a tenth of the 40mg dose I was earlier. The mechanism of action for nsi is under patent and not accessible to anyone except neuralstem so I don’t expect to find out for certain any time soon what may have been causing it.

 

its definitely not as effective the way I’m taking it now, but it’s better than nothing. It’s still a wonderful medication and I’m probably 25 percent more productive and less depressed than I was prior to using it.

 

lastly, I have retained the ability to see colors in full saturation. This doesn’t appear to fade even with a full washout. I’m very pleased with that