marce 1 Report post Posted April 13, 2018 Recently was prescribed zoloft for anxiety, my visuals are much worse today and dissociation is high, anyone have any insight? thanks Share this post Link to post Share on other sites
Originally 12 Report post Posted April 15, 2018 tell your doc your symptoms, test other medications, my dude. a lot of people who try SSRI's tend to have an uptick in symptoms. let your doc know what you're experiencing and get a medication that makes your symptoms not so distressful. It's a process and you'll make it. Share this post Link to post Share on other sites
Onemorestep 35 Report post Posted May 8, 2018 Many people with hppd say SSRIs make them worse. This was the case with me. I was on SSRIs most of my life and went off of them right before I got hppd. When I gave them a shot again I tried a low dose of escitalopram for 7 months. I came off of it due to sexual side effects and noticed that I immediately started feeling better. I was able to fully withdraw in a weeks time which, in my past experience, would normally be too fast and would send me into a depressive episode. I don’t think I was permanently hurt by trying them though. On the the flip side, there are people with hppd that SSRIs have helped. My understanding of the mechanism is it is the eventual downregulation of certain serotonin receptors such as 5ht2a that cause a big part of the antidepressant effect. That and increased bdnf after sustained use. This does take time, however. One to two months on the drug. Before that, many “normal” people can even experience feeling worse. If you think it is worth it to try, give it a shot. Otherwise discontinue and try something else. There are plenty of things that can help reduce 5ht2a and raise bdnf that aren’t SSRIs. I believe selfhacked has an entire page about the receptor and how to influence it—I like the page but it should be cautioned that some things they talk about are not safe for those with hppd such as using psychedelics to downregulate. Also feverfew. Don’t take that. Hope le you find some relief soon. oms 1 Share this post Link to post Share on other sites
justhere 0 Report post Posted May 8, 2018 Hmm I wonder what happened in my case. I took the same ssri for years after hppd with no issue and then back in August decided to get back on the same one again-as I’ve said a few times around here this has caused a major flare up that is still going on almost eighth months later. After the flare up started (within two days of startIng) I immediately stopped. Ironically when I first got hppd and didn’t know what it was I was prescribed both Paxil and Abilify with no issues and may’ve even ameliorated some early “head” symptoms. Wonder if I stayed on the ssri this time around the spike would’ve dissipated by now... Share this post Link to post Share on other sites
rafiki 6 Report post Posted May 9, 2018 (edited) SSRIs have worsened my HPPD symptoms. I only took them for 5 days and a month later they're still fairly severe. Hoping they'll fade with time again. Edited May 10, 2018 by rafiki Share this post Link to post Share on other sites
TheMythos 51 Report post Posted May 17, 2018 On 5/8/2018 at 2:16 AM, Onemorestep said: Many people with hppd say SSRIs make them worse. This was the case with me. I was on SSRIs most of my life and went off of them right before I got hppd. When I gave them a shot again I tried a low dose of escitalopram for 7 months. I came off of it due to sexual side effects and noticed that I immediately started feeling better. I was able to fully withdraw in a weeks time which, in my past experience, would normally be too fast and would send me into a depressive episode. I don’t think I was permanently hurt by trying them though. On the the flip side, there are people with hppd that SSRIs have helped. My understanding of the mechanism is it is the eventual downregulation of certain serotonin receptors such as 5ht2a that cause a big part of the antidepressant effect. That and increased bdnf after sustained use. This does take time, however. One to two months on the drug. Before that, many “normal” people can even experience feeling worse. If you think it is worth it to try, give it a shot. Otherwise discontinue and try something else. There are plenty of things that can help reduce 5ht2a and raise bdnf that aren’t SSRIs. I believe selfhacked has an entire page about the receptor and how to influence it—I like the page but it should be cautioned that some things they talk about are not safe for those with hppd such as using psychedelics to downregulate. Also feverfew. Don’t take that. Hope le you find some relief soon. oms They also promote neuroplasticity in the hippocampus. Share this post Link to post Share on other sites
marce 1 Report post Posted May 22, 2018 On 5/7/2018 at 11:16 PM, Onemorestep said: Many people with hppd say SSRIs make them worse. This was the case with me. I was on SSRIs most of my life and went off of them right before I got hppd. When I gave them a shot again I tried a low dose of escitalopram for 7 months. I came off of it due to sexual side effects and noticed that I immediately started feeling better. I was able to fully withdraw in a weeks time which, in my past experience, would normally be too fast and would send me into a depressive episode. I don’t think I was permanently hurt by trying them though. On the the flip side, there are people with hppd that SSRIs have helped. My understanding of the mechanism is it is the eventual downregulation of certain serotonin receptors such as 5ht2a that cause a big part of the antidepressant effect. That and increased bdnf after sustained use. This does take time, however. One to two months on the drug. Before that, many “normal” people can even experience feeling worse. If you think it is worth it to try, give it a shot. Otherwise discontinue and try something else. There are plenty of things that can help reduce 5ht2a and raise bdnf that aren’t SSRIs. I believe selfhacked has an entire page about the receptor and how to influence it—I like the page but it should be cautioned that some things they talk about are not safe for those with hppd such as using psychedelics to downregulate. Also feverfew. Don’t take that. Hope le you find some relief soon. oms Thank you for your insight, im doing better now. I have since stopped taking zoloft, i was also experiencing sexual side affects and they have since ceased. No long term issues were caused by zoloft im doing well. Ill check out selfhacked sounds interesting! Share this post Link to post Share on other sites
marce 1 Report post Posted May 22, 2018 Thanks for all the help everyone, love this community, were all in this together! 1 Share this post Link to post Share on other sites
