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    • By Bursting Aura
      Some research I found on anti-depressants efficacy and comparisons with placebo. Worth a read.
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172306/ 
       From Harvard
      Antidepressants and the Placebo Effect
      Even the small statistical difference between antidepressants and placebos may be an enhanced placebo effect, due to the fact that most patients and doctors in clinical trials successfully break blind. The serotonin theory is as close as any theory in the history of science to having been proved wrong. Instead of curing depression, popular antidepressants may induce a biological vulnerability making people more likely to become depressed in the future.

      The most commonly prescribed antidepressants are SSRIs, drugs that are supposed to selectively target the neurotransmitter serotonin. But there is another antidepressant that has a very different mode of action. It is called tianeptine, and it has been approved for prescription as an antidepressant by the French drug regulatory agency. Tianeptine is an SSRE, a selective serotonin reuptake enhancer. Instead of increasing the amount of serotonin in the brain, it is supposed to decrease it. If the theory that depression is caused by a deficiency of serotonin were correct, we would expect to make depression worse. But it doesn’t. In clinical trials comparing the effects of tianeptine to those of SSRIs and tricyclic antidepressants, 63% of patients show significant improvement (defined as a 50% reduction in symptoms), the same response rate that is found for SSRIs, NDRIs, and tricyclics, in this type of trial (Wagstaff, Ormrod, & Spencer, 2001). It simply does not matter what is in the medication – it might increase serotonin, decrease it, or have no effect on serotonin at all. The effect on depression is the same.
      What do you call pills, the effects of which are independent of their chemical composition? I call them “placebos.”
       
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592645/ 
      From Duke and Brown University
      Antidepressants versus placebo in major depression: an overview
      As of now, antidepressant clinical trials have an effect size of 0.30, which, although similar to the effects of treatments for many other chronic illnesses, such as hypertension, asthma and diabetes, is less than impressive.
       
      https://www.ncbi.nlm.nih.gov/pubmed/22147715 
      Comparative benefits and harms of second-generation antidepressants for treating major depressive disorder: an updated meta-analysis.
      Meta-analyses and mixed-treatment comparisons of response to treatment and weighted mean differences were conducted on specific scales to rate depression. On the basis of 234 studies, no clinically relevant differences in efficacy or effectiveness were detected for the treatment of acute, continuation, and maintenance phases of MDD. 
       
       
    • By Bursting Aura
      Omega 3's are mentioned a lot for there importance for brain health. Vitamin D can also pass the blood-brain barrier, so it should be investigated for mental health also. I drove over some papers on vitamin D and depression since yesterday, so I will share some of those here. Depression impacts quality of life and it is usually implicated to be self-caused. According to science, depression can be biological, therefore depression is not always a lack of spiritual perspective or a case of "bad" vibes. My conclusion from these papers is that most cases of depression are very situational. Vitamin D deficiencies are not rare, and can potentially have a healing affect with some cases, similar to anti-depressants. The optimal ways to get vitamin D in my opinion, is sunshine and mushrooms. I would stay away from raw mushrooms due to carcinogens reported in the literature. heat destroys them though. https://www.ncbi.nlm.nih.gov/pubmed/2132000
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751336/
      Efficacy of vitamin D supplementation in depression in adults: a systematic review protocol
      "The efficacy of vitamin D supplementation in depression has raised lots of concern. Vitamin D is considered as a neurosteroid [56], and now it is attested that vitamin D metabolites can cross the blood–brain barrier [34]. Because of the widespread presence of vitamin D receptor in areas of the brain including the hippocampus which is associated with the development of depression [23], it could be speculated that there is a clinical effect of vitamin D on depression."
      https://www.ncbi.nlm.nih.gov/pubmed/26680471
      Vitamin D in anxiety and affective disorders.
      "Reduced levels of vitamin or its metabolites have been reported in various psychiatric disorders. Insufficient levels of vitamin D in depressive patients have been confirmed by many authors. Significantly lower levels of calcidiol (vitamin D) were found in men and women with depression as well as in age matched patients with anxiety disorders.
      https://www.ncbi.nlm.nih.gov/pubmed/25713056
      Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior.
      "Serotonin regulates a wide variety of brain functions and behaviors. Here, we synthesize previous findings that serotonin regulates executive function, sensory gating, and social behavior and that attention deficit hyperactivity disorder, bipolar disorder, schizophrenia, and impulsive behavior all share in common defects in these functions. It has remained unclear why supplementation with omega-3 fatty acids and vitamin D improve cognitive function and behavior in these brain disorder"
    • By justaman
      I took hppd about 2 months ago and ever since I’ve been very aware of what I’m seeing. Like at night when I’m in the car driving, I’m not sure if it’s been there before but street lights or any sort of light kinda has a glare to it, like very shiny and has like a glow to it. I’ve noticed that when I look at the moon. There’s another moon next to it but half of the size, like a glare. I suck at explaining but am I getting hppd or is all this normal? I’ve been stressing over This for a while now and I’m going to a psychologist to get checked out. 
       
      I forgot to mention that I only taken lsd once. I’ve only smoked weed before . 
    • By HDDeer
      Hey guys,
      My doctor prescribed me lamictal yesterday and as pretty much all of you know, it's one of the more highly regarded medication out there for this condition.
      My hppd is actually very bearable, the only time I struggle is when I'm alone in the house where the lsd trip happened, which leads me to a few questions.
      If I decide to take it, and my hppd gets better/worse/stays the same, if I stop taking it will I return to baseline? Has anyone else taken this med? 
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HDDeer

Reassurance

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This is mainly to the newcomers like myself. For those of you just entering your days of hppd, take it from someone who also hasnt had it for very long, ive only had it for 3 months. The first month to months could very well be a hellish ride straight to satans throne. But one thing id tell you is to not lose hope, insert yourself into discussions with friends and on forums(not just about hppd but anything) take some recommended vitamins like vitamin d3 and b complex and magnesium, get a therapist you can talk to and stay active, all these things will help you get better. While my visual symptoms have not subsided, my physical symptoms on the other hand have. Ive always had social anxiety tho, so for the most part i would say i definitely feel like myself again. I attempted suicide in my first month and its now my third month and im so glad i never did. If theres three things of most importance i could tell you to do 

1. Acceptance(accept this is your life as of right now, you cant dwell on the fact you MIGHT have this for the rest of your life because you also MIGHT NOT. My girlfriend told me i just need to take it one day at a time, we live day by day not month by month or day by month, you dont know if youll have this tomorrow or a month from now or a year, which leads to my second)

2. Never give up hope (Accepting that you have it in my opinion is a great step to recovery. But also being hopeful in the possibility of recovery is very important) 

Acceptance and being positive/hopeful are two great things to feel towards hppd. Its at that point imo you can feel true improvement and recovery.

3. CEASE ALL DRUGS. I cant stress that one enough, let your brain rest.

Those in my opinion are the three best things to do when faced with hppd. Granted i may have it milder than a lot of hppders but i do want you guys to know i havent smoked or dosed since the onset, i drank maybe 3 or 4 times(avoid that too if you can) i also have a foot injury right now but most of my improvement came when i was going to the gym and running and sweating like a dog. Hppd isnt the end, but in a lot of ways its an eye opener. 

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Great advice.

I know months can feel like decades in that early stage. I vividly remember it myself... But it is essential to give yourself the best possible chance to recover... Try and remove as much stress from your life as possible. If you need to take time off, do it... If you need to lock yourself in your room, do it... Whatever helps with stress... You can quickly get your life back on track once you recover or learn to deal with this.

I would also add that self blame/self loathing is great fuel for stress and anxiety. If at all possible, forgive yourself for taking risks with drugs and realise that no amount of wishing you hadn't done something will ever make it so... It's wasted energy and added stress, so just forgive yourself for doing something that millions of others do, learn and move on. (easy said than done, i know!).

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Excellent post.  Couldn't agree more with items 1-3.  Jay's point regarding self blame is excellent as well. 

One thing, even if you're symptoms don't seem bad at first and your life isn't hell, proceed with caution.  When I stopped using I was kind of stumbling out of a long term psychedelic stupor.  The symptoms (visuals)  I had were initially kind of reassuring.  It wasn't until the years started to go by that I realized it wasn't going away.  Sobriety at the first sign, good or bad is important IMHO.

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