Sign in to follow this  
Followers 0

3 day escitalopram trial and some questions

4 posts in this topic

Approximately one week ago I saw a psychiatrist for the first time and was prescribed escitalopram and risperidone (which I have yet to try for obvious reasons) for MDD/panic disorder and mild/residual psychotic symptoms, respectively. On thursday I decided to start the escitalopram @ 2.5mg per day in the morning after careful consideration. Here's a short chronicle of what happened:


Thursday, April 2nd (Day 1): Dose @ 8:20 AM as I'm leaving for work and class. At approximately 9:15 AM I start to feel it come on (sinus/head pressure, random "tingles" in arms and face, possibly placebo). Around 10:30 AM I start feeling a sense of calm and indifference, my mood is completely neutral. I feel neither depressed nor happy, a not necessarily pleasent in between, possibly placebo. My face, particularly around my eyes starts to feel tight, as if I were squinting or just came in from the cold, this lasts for another 3 or so hours. I'm sitting in my final class of the day, around 2:00 PM. I feel extremely fatigued and begin to noticeably nod off and almost fall asleep in class. I drink some water and focus my attention on the lecture. Still feel extremely fatigued though not to the extent of nearly passing out. Class ends and I go back to work for a few hours. The bus ride home is extremely hard as the fatigue and drowsiness will not go away. Food, beverage and homework alleviate this. I finally crawl into bed around 2:00 AM. The sleep is deep and beautiful with insanely vivid dreams (I awoke thinking I was still in one until my 2nd alarm went off). Visual symptoms remained unaffected thoughout the day, neither worsened or lessened by the escitalopram. There was also some mild anxiolytic effects.


Friday, April 3rd (Day 2): Dose @ 8:20 AM again as i leave for work and class. Same come up as before. Same neutral mood as before. A little before my final class of the day at 2:00pm I begin to feel a weird tension in my shoulders, arms and hips/thighs, similar to the soreness after a good workout. It isn't painful, but it is very unpleasent. I also get a headache on the left of my head (I've had these before though). I start to get a very weird feeling thoughout my body in addition to the muscle tension, like a buzz feeling, very similar to how I feel during panic attacks. I feel the need to get up and move. I excuse myself from the class and go to the restroom where I splash water on my face which helps to calm me down and I return to class. I notice my pupils are extremely dilated and my cheeks appear somewhat rosy. I also feel very warm in an unpleasant way. On the bus ride home I feel very, very fatigued/drowsy again and it is hard to keep from nodding off.  Again, some food helps to alleviate this. I go to bed around 4am and sleep for perhaps 4 hours and the sleep is nowhere near as pleasent as it was on the first night, surprisingly I don't feel too tired. I also woke up with very bad cramps and had to use the restroom almost immediately after waking up. The visuals remained the same as they had been all day, no worse or better.


Saturday, April 4th (Day 3): I dose around 12:15pm because I had slept later than usual from the previous night (bed at 4am followed by an awakening around 6:30, restless laying in bed for awhile followed by dosing back off again around 10:00am) and I just really wasn't feel too into taking the escitalopram again. Much the same as the first day, little to no adverse SE like I had the day before. I do notice a strange lightheadedness and feel sort of spaced out the whole day. There is also no fatigue like there had been the previous two days. I go about my saturday as usual. Late into the night I start feeling very strange, can't tell if it's the escitalopram or the lack of sleep. I almost feel delirious, very out of it and very on edge. I also start to feel that extreme drowsiness and fatigue again, though this is probably more because of the lack of sleep then the meds. I crawl in bed around 4:30am. I wake around 6:30 feeling unpleasently energetic, agitated and spaced out (the agitation was likely because of the lack of sleep). I toss and turn for awhile before getting up. After being up for awhile, drowsiness and fatigue hits like a train. I almost literally crawl back to bed and sleep untl 11:00am.


And that brings us to today. The visuals today were much worse, particularly the trailing and ghosting (i.e. double vision). The trailing today was much more noticeable, distinct, pronounced and longer lasting. The ghosting is also much more pronounced and severe. Reading text on my monitor is extremely straining and hard on my eyes now because the ghosting is so bad. Because of these reactions I am now thoroughly convinced I have HPPD and as a result, I will not be continuing to use the escitalopram. As much as I would like to be rid of the depression, I don't think I could handle potentially 4 weeks of worsening visuals just for some reduction in the depression. Not only that, by my anxiety now is linked to the visuals, so an increase in visuals will no doubt cause an increase in anxiety. Further, I also won't be trying the risperidone as that will no doubt worsen symptoms much more than the escitalopram. I also think the insomnia is linked to possible precipitation of a brief hypomanic episode by the escitalopram.


I'll be seening my psychiatrist again in a few weeks, so how should I go about telling him I think I have HPPD? I don't want to come off as dismissive of his diagnoses, which I feel are correct, or as resistant to treatment. I'm also fairly certain that he doesn't know about HPPD and if he dose, has very little experience with treating it.


Further, are there any antidepressants that won't interfere significantly with HPPD that I could recommend to my doctor? I would assume they wouldn't be anything that has to do with serotonin, but it seems like all the common ADs have some sort of effect on serotonin. Also, how long will it take for the escitalopram to clear my system and for the visuals to return to what they had been before?




Share this post

Link to post
Share on other sites

Wellbutrin (also goes by other names) might be something to look at for the depression. It should be HPPD-safe since it works on the dopamine rather than serotonin system.


Share this post

Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  
Followers 0

  • Similar Content

    • By tlehmbecker
      So, after a hospitalization for a suicide attempt I've been put on 10mg Abilify (aripiprazole) and have been taking it daily.
      Haven't noticed my symptoms getting worse. Perhaps slightly, but nothing unbearable at this point. 
      Additionally I have tried 1:1 THC:CBD weed with no worsening of symptoms. This suggests to me at least that the mechanism behind my HPPD is entirely different than the common hypotheses.
    • By neverwarned
      Hello Im new here and have never posted on a forum in my life. I guess I will start off with my story and what happened .. I have always had a depression and anxiety disorder for as long as I can remember  when I was 15 I was put on Zoloft I also smoked pot for 10 years or so . when I was 25 I went on disability because my anxiety was way to hard to deal with. in mid may 2015 I tapered off Zoloft slowly and wow It was hell coming off but and I felt like I was a totally new person and wow my vision seemed to have gotten so much better I felt like I was in a new world, I stopped taking the Zoloft when my then soon to be wife went to Texas to visit her family for a year, so I thought it was a perfect time to come off the Zoloft, well she was gone for a month and I was feeling social like I never had felt that before and I opened a facebook account and of course the first person I looked for was her, and bam her profile pic was of her and another man , shit we were together for ten years, so my depression hit a all time high and the doc wanted me to go on Effexor but my insurance didn't cover it so I went back on the Zoloft in October 2015 and 2 weeks into it at 25mg I started to notice a change in my vision I was seeing a dark line on the left side of objects so I said "no way" the Zoloft is messing up my vision ,so I stopped taking it and was hoping that my vision would return back to good , well it continued to get worse, I then started to get sensitive to light and that dark line on the left side of things was getting worse and turned into a ghost image like seeing double but with each eye , then I started to notice trailing vision , negative after images , slight snow vision , glowing colors , shaking and blurred vision . and I could not stay awake for the life of me and I feel like im seeing threw video cameras and I have brain fog I feel like I am not in my own body sometime and when I look at the ground when im walking It looks like im walking on a round globe kinda.... light colored parts of peaples faces seem to pop out at me and the ghost image makes everyone look like they have three eyes.  wtf this is crazy ,... now I have tinnitus ,  this has been going on 3 1/2 months now and Ive had cat and mri scans and blood test and all have come up clean . my doctor said I would have to be on drugs to be having these symtoms. 
    • By lysandre

      Hello everyone. My name is Sébastien, i'm 37 years old and I live in France. I've always been very anxious but i'm a in a terrible state since 1 month.
      I'm suffering from depression/anxiety since 4 months. (i've been on ativan since 2 months)
      So I've been on Paxil for 1 week at 10mg, but it gave me severe urinary retention. I took it for 6 days and one day at 5mg.
      I was having an appointment with a psychiatrist the day after i stopped Paxil (so the next day), and he advice me to take Zoloft (Sertralin) beacause it was much more tolerable and less side effects on libido. (sorry for my terrible english)
      I took half dose of Zoloft (25mg) on Thursday 9. This night, I went to bed and as soon as I closed my eyes, an intense light activity appeared, with lot of flashes and lights, dots, lots of "pictures" at a very high speed etc. I've also had kind of "hallucinations". I've had my psychiatrist on the phone and he said that these kind of side effects were unknown with Zoloft etc., my pharmacist said that was normal, beginning of an antidepressant treatment. I took Zoloft for 4 days and now i'm no longer taken it.
      Now since 1 month i have
      Light sensitivity
      Negative After images
      More floaters than before
      I know that my symptoms are not as severe as many of you...
      I've seen 2 ophtalmologist, 1 neurologist; had a brain scanner and MRI, everything is "normal".
      These symptoms seems to improve a little bit but i drank so much on New years Eve... and now they are worse, especially the negative after images. No More alcohol for me.
      All of this doesn't help my anxiety, I hate my psychiatrist and I hate my self, was just so dumb to take this poison, now i'm very upset and scared.
      I take vitamins, magnesium (300mg) and Omega 3 fish oil (1050 EPA/day) since 1 week
      What do you think about that ? Is there any people who had experienced similar symptoms with SSRIs ? 
      Thanks a lot for your consideration.
    • By alice-acid
      I know there is generally agreement that SSRIs can worsen symptoms and should be avoided where possible, but I haven't had any HPPD symptoms outside of visual snow and some other mild visual disturbances when VERY hungover (halos and starbursts and trails etc) for a few years now. I have started really struggling with other mental health issues though recently, I hesitate to say depression as it seems to come in some pretty extreme 'episodes' of feeling suicidal, rather than a more permanent low mood. But either way my Dr has asked me if I want SSRIs (no surprises there). Would it be really stupid to day yes? I know it's up to me at the end of the day but I can't find much on here about them re-awakening symptoms like anesthetic can do, so I was just wondering people's opinions. 
    • By Chiggs17
      For those of you who have tried SSRI's have they increased your visual symptoms or decreased them? Or had no apparent effect? I'm considering changing my medication since it seems like a lot of people are saying SSRI's make HPPD worse. Also if it is making my symptoms worse should they return to a baseline when I go off them? I went on the ssri around the same time my HPPd symtoms began so it's my hope that they might die down a bit if I discontinue the drugs. Currently on 20mg lexapro