Jump to content
Hallucinogen Persisting Perception Disorder (HPPD) Support Forum
Sign in to follow this  
andrewcb

Question about Memantine.

Recommended Posts

My pyshiatry give me memantine "for the study" , i can say make my DP/DR 5-10% worse, memantiine is an antagonist NMDA, like ketamine or PCP (dissociative drugs)

i ask about Naltrexone with him but not want give me that, i havean hunh about naltrexone for fix in part my DP/DR 

some pepople say naltrexone is good for DP/DR

 

in teoría DP/DR is like salvia dissociation, salvia is an K-opiod potent agonist, naltrexone is an parcial k-opiod antagonist and in theory have sense 

is the same think with some opiods like suboxone

we can try with that, can be the interruptor for a part of the dissociation de Kappa opioide receptors

Share this post


Link to post
Share on other sites

What dosage of memantine were you on? Did you ever get a chance to triturate up to like 20mg? Yeah the reason I was worried about it worsening my dp/dr is because it is a dissociative, I really don't want to reverse any progress I have made on my dp/dr lol. 

 

Also, I have used LDN, 4.5mg naltrexone. Sadly it did nothing for me. But in all fairness I was addicted to opioids for a long time and even went through a year on Subutex so I am obviously not going to be the best responder to Naltrexone with all the downregulation I have been through. Naltrexone is not a controlled substance and can be purchased online legally. FWIW, Subutex and other opioids such as hydrocodone and oxycontin did help my dp/dr out tremendously. I could see how Naltrexone could help with dp/dr if you have never abused opioids before. From my understand Naltrexone temporarily blocks opioid receptors which is why you want to take it at night and when the Naltrexone starts to detach from these receptors the receptors become super sensitive to your natural opioids. It also suppose to cause a temporary upregulation in opioid receptors. 

 

Hope that helps! 

Share this post


Link to post
Share on other sites

What dosage of memantine were you on? Did you ever get a chance to triturate up to like 20mg? Yeah the reason I was worried about it worsening my dp/dr is because it is a dissociative, I really don't want to reverse any progress I have made on my dp/dr lol. 

 

Also, I have used LDN, 4.5mg naltrexone. Sadly it did nothing for me. But in all fairness I was addicted to opioids for a long time and even went through a year on Subutex so I am obviously not going to be the best responder to Naltrexone with all the downregulation I have been through. Naltrexone is not a controlled substance and can be purchased online legally. FWIW, Subutex and other opioids such as hydrocodone and oxycontin did help my dp/dr out tremendously. I could see how Naltrexone could help with dp/dr if you have never abused opioids before. From my understand Naltrexone temporarily blocks opioid receptors which is why you want to take it at night and when the Naltrexone starts to detach from these receptors the receptors become super sensitive to your natural opioids. It also suppose to cause a temporary upregulation in opioid receptors. 

 

Hope that helps! 

i dont remememb can be

opioids can be good no only for the antagonisma in kappa receptor, togheter anxiety

but is you DP/DR is caussed by anxiety can be helpo

i have DP and DR but 0% anxiety

im in peace

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Sign in to follow this  

×
×
  • Create New...

Important Information

By using this site, you agree to our Terms of Use.