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Etizolam


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Yeah, 1mg was my usual dose. My first time taking Etizolam I took .5 and didn't feel much either interestingly, so I thought, hmm this must be weak, so I took another 2mg and was unable to walk properly.

 

You should be able to feel 1mg in about an hour. Under .5 is a very small dose, if it was .4 then that's equivalent to 4mg Diazepam, which isn't much. There's also other considerations to take into account such as a full/empty stomach, and if you broke a bit of the tablet off then there's always the possibility that the active is not spread out evenly throughout the pill. 

 

I'd recommend you give it a try with 1mg on an empty stomach and see how you feel. 1mg won't knock you out or anything crazy. 1mg is the equivalent to .5 of Clonazepam so it's not too heavy.

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  • 1 month later...

I just tried Etizolam today (Etilaam blister packs).

Some quick observations:

  • At 0.5mg this feels like a very "clean" benzo (yes thieno, whatever). Proper anxiolysis. No cognitive impairment.. actually I might've noticed some increased lucidity. No sedation at this dose either. Definitely my best benzo experience ever. Visuals were also improved (haven't been able to see the patterns in the wallpaper for 3 weeks; this was the first time I was able to again).
  • Added 0.5mg at T+3:00. Sedation become quite apparent, yet still not as bad as other benzos I've tried (Oxazepam, Prazepam, Diazepam).
    At this point I start noticing mild cognitive impairment such as writing "through" instead of "throw". I don't particularly like this feeling; but it's bearable.
  • I've been able to drink 2 cups of coffee without any anxiogenesis. Awesome, awesome, awesome.

In conclusion it seems to me that 1mg is too much for me; I should've known this as I already seem to respond strongly to benzos. 0.5mg was not recreational, yet made me feel much better. I don't plan to use this any more than thrice a week; addiction/tolerance/withdrawal are things I'd like to avoid. I'll probably just use it every Sunday like I did with Phenibut, and use occasionally as-needed.

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ODISA what visuals symptoms were improved if you don't mind adding and to what degree? 

Would you reccomend this to someone who has mild-severe GAD as a relief? I personally don't take benzos anymore because of this evident withdrawal symptoms and tolerance building aspects. 

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  • 1 month later...

Sorry for my english pp but time to write some of my own experiences about this new RCS. And a question about a new one ^^

 

Sins this topic begins to develop into a tread where new benzo research chemicals are discussed. let me ask about Flubromazepam. Dit anyone tried this yet? It seems interesting but its kinda expensive for an RC at the moment. So i dont know if i should buy / waste my money on it already lol. To me benzos work great against anxiety and \visualsnow. So i like to experiment with the new ones.

 

Ive tried Etilaan(Etizolam is just the brand)for a few weeks (when i had no clonazepam anymore lol). Its was a little hard in the beginning because of the short half life. But in the end i'm very positive about Etilaan. I tried two times of pills, a blue one from 1 mg (works fine) and a 1.2mg variant witch is kinda beige(thats a color in English right, srry if not). I have also a little experience with Diclazepam 1 MG sins a couple of days. But i find those kinda weak. in my opinion and a friend of mine too,,

I gave him 4 pills of 1 mg and he was also reporting that its very weak according to diazepam(cheap lol).

(i have some benzo tolerance, but the other person not).

 

I think 2 mg dicla = 10 mg blue roche dia (internet says 1 = 1 lol).

So i just ordered pyrozelam, any opinions from what dose the med works ok in comparison to the other RCS(asks in public)?

 

For me Etilaan 1mg works good against visuals and all the standard things witch come with hppd, 2 mg almost e mobilizes my symtomes but is too high. I get holes in my brain from this stuff  when taking it like other benzo's(so almost on daily baise).

Diclazepam: i need to take at least 2 mg... to feel any real effect.

 

Thats it already ^^

Thanks

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Yeah it's best used once or twice a week, I'd say twice at most, in the form of maybe one dose mid-week and one dose at the weekend, or maybe a dose Saturday and a dose Sunday, most people don't experience problems with this kind of usage. 

The thing is with Benzo's is that it's so easy to get into the pattern of taking them more and more often, after all, all you have to do is swallow a pill, that's 1 second of effort for a day of anxiety and symptom relief. Be very careful, monitor your usage if possible as due to the nature of Benzo's and their effect on memory, it is quite easy to forget you have taken one on a certain day and end up getting into nasty habits.

 

Not to demonize them too much, used sparingly they are great and this is something I practice myself, yet I never feel I 'need' them, use them with respect and you should be fine. I'd hate to see anyone go through severe Benzo withdrawal just because these are currently legal and easy to obtain.

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  • 2 weeks later...

I'm still taking these (etizolam) once in a while (perhaps slightly less than once a week on average). I find them mild/moderately effective at 1mg doses. Once or twice I have taken 1mg before teaching (i teach a ''recital class'' at university) and I didn't feel any real cognitive impairment.

 

My personal problem with benzos is that the times when I need anxiolysis/symptom relief the most are usually when I need to perform academically. Benzos and academia don't really mix well, so I keep the dosages low.

I took 15mg oxazepam before my last two exams (sorry for going slightly off topic here). At the oral exam it worked well, since I was already quite ''pumped'' and the whole ordeal was over within ~25 minutes, meaning that I had no problem staying focused and sharp. For the written exam (4 hours) it turned out to be less than ideal, since I began feeling quite sluggish and couldn't really keep up the pace like I used to.

 

All in all, however, using benzos is probably preferrable to feeling like I'm floating above my own body in a stressful situation. But it is far from perfect! 

 

For the last month I've only used etizolam (not oxazepam, like I used to. I still have some left, though, so it is not out of necessity as such). Overall I find that:

  • Oxazepam is perhaps slightly more effective wrt anxiolysis
  • Etizolam leaves me less ''inebriated'', able to function essentially normally.
  • Etizolam feels less ''relaxing'' (sometimes even slightly ''buzzy'' at first)
  • Oxazepam is somewhat more effective at relieving my worst symptoms: Dizziness and strange head sensations.
All in all, it's close to a tie. Both are very much preferrable to (for instance) alprazolam, which leaves me dumb and slightly depressed (though mostly anxiety-free).
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  • 3 weeks later...

I have done extensive self-experimentation with Etizolam ever since I discovered it about 6 months ago, I find that it works best when taken for periods of time as opposed to dosing occasionally.

 

When I have a break from Etizolam for say a week or 2, and then take 1MG, the hypnotic effect is very apparent and it slows me down quite a lot, now, if I take 1MG 2x per day for a week or so, it somehow becomes more effective the longer I use it. There are studies to this effect too which I believe I linked to somewhere in this thread. Etizolam definitely increases in effects the longer you take it, although with that you have to be careful, I've never had any withdrawal from Etizolam or any other Benzo, and I've read that a majority of people never experience withdrawal, but the fact that Etizolam has been shown not to downregulate alpha-1 subtypes and upregulate alpha-2 subtypes is quite promising,

 

Really, the only withdrawal symptom I've noticed is some rebound anxiety which is to be expected when you're taking something that nullifies anxiety, and some neck pain. In any case, I have in my posession around 400 1mg Etizolam pellets, and I'm controlling my use quite nicely, I had a weeks break, then took some for a couple of days, then had another weeks break and have currently been taking them for a few days again to help me through a rough patch.

 

In any case, I have around 350 branded and boxed Etizest Etizolam in my posession that were very cheap (The pink Etizest are far better than the loose pressed blue generics). I have not noticed any tolerance whatsoever or any withdrawal to speak of, as long as I'm careful then I can't see any problems. 

 

Etizolam has been THE HPPD killer for me, I feel back to normal on these. It completely kills all of my visuals aside from some very fine residual visual snow, and depersonalization is almost none-existent. It's a shame really, if I could take 2mg a day indefinately my life would be great.

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  • 2 weeks later...

My pleasure :)

I suppose we all react differently to medications, for example Xanax makes me anxious and agitated and leaves me unable to sleep. But yes, it's been a wonder medication for me, when I take it I experience 80-100 percent symptom remission, absolutely no tolerance noted as of yet.

I think there's more to Etizolam than meets the eye, the fact it shows SNRI type effects in EEG scans explains why I'm often quite productive on it, and the seretogenic activity may play a part in why it's been so useful for my personal HPPD pathogenesis, it fascinates me how it doesn't down regulate alpha 1 subtypes and up regulates alpha 2 subtypes, along with the fact in studies no tolerance to the anticonvulsant effect was noted, no cognitive problems in a 4 week trial and the fact it became more effective the longer one took it. Very paradoxical for a BZD agonist.

I've recently been trying Flubromazepam which has been amazing for visuals. I'm quite interested in benzodiazepines and their various analogues.

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So am I :-) .

As for alprazolam; it has a strange (albeit different) effect on me as well. It leaves me depressed and 'withdrawn' even at low doses. I believe I've mentioned this earlier in the thread.

 

I have a tendency to experience some anxiety during the "come-up" phase with benzodiazepines. Etizolam has been the gentlest in this respect (compared to oxazepam, alprazolam & lorazepam).

 

I agree completely with the productivity aspect!

I used some benzodiazepines when studying for an important oral exam a couple of months ago. Often I would be going through mathematical derivations in front of a few peers several hours a day during this period, which meant that it was a fine time to test the effects of benzodiazepines on my performance. I found that I was able to be very productive and clear-thinking with etizolam (more so than in my usual 'sober' HPPD state, I'd say) whereas oxazepam left me feeling somewhat lethargic and unfocused (not too bad, but unmistakable).

As I mentioned earlier, etizolam doesn't seem to affect my ability to teach either.

 

Initially I was somewhat worried about the SNRI action, though, since all serotonergics seem like "dangerous territory" to me as a HPPD sufferer. No obvious repercussions as of yet.

 

wrt flubromazepam: I'd be very interested in hearing about your experiences with this compound - and other promising medications, for that matter. Have you done any reading regarding the potential for physical dependency, tolerance etc?

 

Edit:

 

Ive tried Etilaan(Etizolam is just the brand)for a few weeks 

Just to clear things up; it's the other way around. Quoting from Wikipedia: "Etizolam (marketed under the brand name Etilaam, Etizest, Etizola, Sedekopan, Pasaden or Depas)"
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Yeah, Etizolam is sort of a lone ranger in the world of Benzodiazepines and their various analogues, I find myself much more productive, alert and it actually makes me want to do things, participate in my hobbies, socialise and actually enjoy what I'm doing. Maybe this has something to do with the supposed norepinephrine release/reuptake, however I am unsure.

 

All I know is Etizolam, as far as Benzodiazepine's go, is #1 for me. Just an FYI to everyone, if you'd like to try Etizolam, get the boxed and blistered Etizest brand. They seem to be far superior to the blue generics and Intas Etiilam, which I believe are slightly under-dosed.

 

Flubromazepam - An interesting BZD analogue indeed, as one might assume from the chemical structure it is a Rohypnol type modification of Bromazepam, although doesn't share the same effects. My experiences with it, and some information about the compound are as follows:

 

If you navigate to the Wikipedia entry on Flubromazepam, you will find a research paper detailing the metabolites and information about half lives, along with other information I do not understand. It is the second link under 'references'.

 

In a nutshell, Flubromazepam has an estimated half life of 106 hours, and from my own personal experience, is better than Etizolam for reducing visuals, although not for functionality. It has a VERY pronounced anxiolytic effect, and a moderate muscle relaxant effect, although drowsiness was not an issue and so the compound is not very hypnotic.

 

I have experimented with the compound at dosages of 4mg, 8mg and 12mg. 4mg produced a reduction in visuals (30-50%) and a reduction in anxiety (50-80%) that lasted about 2 days. At a dosage of 8mg, it was perfection. A strong reduction in symptoms spectrum wide, DP/DR, anxiety and visuals all decreased by around the 60-80% mark for 3 days, but be careful, this one lasts a hell of a long time, so start out low.

 

Flubromazepam doesn't feel quite as functional as Etizolam, and takes about 3 hours to 'come up', however there were no unwanted side effects such as bad amnesia, drunken-ness, loss of motor co ordination etc.

 

Although not much research has been done on the compound, I'd hazard a guess that it has strong anxiolytic and anticonvulsant properties with moderate muscle relaxant properties.

 

The only way I can describe it without one actually ingesting it, would be a cross between Clonazepam, Diazepam and Etizolam. Although it is quite expensive at the moment I am having lovely results with it.

 

No studies or information on addiction at the moment, but I'd guess it would share the same addiction and withdrawal characteristics as the other long-acting BZD's.

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  • 1 month later...

I linked to an article on benzodiazepine pharmacodynamics earlier, but odisa told me that the link is inaccessible, so I've uploaded it here:

@Sam93 : You mentioned flubromazepam. I've got my hands on a small sample of 5mg tablets, but I haven't used them yet - and I'm a bit wary due to the small amount of research into this compound. Do you still use it occasionally, and is it still as effective for you? :) 

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Thanks for the information on flubromazepam; I may get it from one of these research chem websites as long as they offer a COA and the site doesn't look suspicious. I personally believe perceptual training, nutrition, and supplementation will be what offers me avail, yet that will take time, perhaps a long time; for now, I need to be at least partially functional to attend classes and so forth. I haven't tried Etizolam yet, but I'm kind of saving it for the occasions that I feel absolutely terrible, or prior to an anxiogenic situation. Flubromazepam seems like something that can offer aid to a student such as myself - I can take it earlier in the day and it will gradually increase in efficacy as the day proceeds and I go from class to class. Upon searching it up, there are a lot of benzo-derivatives around and coming out that I was unaware of. 

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Speaking of interesting benzo-derivatives, I'd be very interested in trying tofisopam. It looks very promising, although the speculated mechanism(s) of action are a bit perplexing to me. It is marketed as an anxiolytic in some countries (Egypt among others).

I didn't get on with Tofisopam, IIRC it made my visuals worse. I forgot/didn't realise that it was the 'only stimulant benzo', as they call it. I couldn't sleep after I took it, which was my purpose. Perhaps the stress of not being able to sleep caused the visuals to become worse. I could try it again and make another report.

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I didn't get on with Tofisopam, IIRC it made my visuals worse. I forgot/didn't realise that it was the 'only stimulant benzo', as they call it. I couldn't sleep after I took it, which was my purpose.

Ah, that's a shame - and a bit worrying. But it does indeed sound like you used it for the wrong purpose :) .

Perhaps the stress of not being able to sleep caused the visuals to become worse. I could try it again and make another report.

If you feel like it doing it, I'd be very interested in hearing about your experience. As would others, I'm sure :) . I'm of course mainly interested in its merits as an anxiolytic.
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