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joejack102 posted a topic in MAIN AND GENERAL FORUMQuick summary: For the last ~20 years, I've had "some disorder," that has similarities to Chronic Fatigue Syndrome (CFS) and other similar syndromes (like Dysautonomia). I used to be EXTREMELY sensitive to ALL HERBS & MEDS. They would have 1,000x's exaggerated effects. ASHWAGANDHA: Used to be a temporary cure for my extreme sensitivities (for 24 hours). CHAMOMILE: Used to do the exact opposite of Ashwagandha; it would INCREASE my sensitives (for 24 hours). AFTER CHOLINE: After I took CDP Choline & Choline Bitartrate extensively, Meds & all herbs no longer work, and I have long-term critical and alarming levels of fatigue & brain fog. Can somebody help me reverse whatever the Choline supplements did to me? The following are POSSIBLY relevant:Acetylcholine Mediated Vasodilatation in the Microcirculation of Patients with Chronic Fatigue Syndromehttp://www.prohealth.com/library/showarticle.cfm?libid=10459 Also, Ashwagnahda is known to "increase the capacity fo muscarinic receptors," so this could be relevant to what is happening as well. Any/all help is much appreciated!!!!!!