jbalsa2

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jbalsa2 last won the day on May 3

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  1. Its actually an antagonist at 5ht2a, although some people have reported worsening of visual symptoms on mirtazapine. So far my visuals are exactly as I would perceive them when I wasn't taking an antidepressant. This medication seems to differ in side effects from person to person, as for me, I'm well immersed in its antidepressant activity, and my hppd symptonology has been left untouched. This could prove useful for people who are depressed and can't take SSRI's due to their hppd.
  2. Hey guys, Just thought I would add a quick post for anyone who's interested. I saw my psych doctor a few days ago, and he's decided to start me on an antidepressant called Mirtazapine. Mirtazapine is a tetracyclic antidepressant, one that is relatively new to the market compared to most tricyclic and SSRI anti depressants. It's day 3 now, and so far I am absolutely loving this medication. I had let my psych doc know that most SSRI's that I have tried have exacerbated my symptoms by a fair margin, and that I had to stop taking them. He gave me this one to try out. As with all anti depressants and HPPD, it does affect the way you perceive the HPPD a little bit, but what separates Mirtazapine from other SSRI's is that Mirtazapine plays nicely with my HPPD. My visual symptoms have not gotten any worse, although the way that my body perceives the HPPD is a little bit different. What i'm loving about this med is that it's pretty much completely taken care of depersonalization and derealization, while also working wonders for my depression and anxiety. I think once you've found a med that tackles DP/DR and anxiety and depression all at the same time, it makes dealing with the visual symptoms a very minor disturbance. Not everyone has had luck with mirtazapine, but I guess im one of the lucky ones here, as it is easily the best medication if taken for my HPPD by a long shot. Just thought I would start a topic as I really believe that this medication is worth a try if you find yourself struggling with DP/DR and anxiety+depression all at the same time. If any of you guys have questions feel free to ask! I'm on 15mg once daily, and il be staying at this dosage for a full month before I titrate. The maximum dosage of this medication is 45mg daily.
  3. @TheMythos my psych doctor is likely going to put me back on benzos for a while, and I think il use that opportunity to test out Keppra. I've also heard success stories of people using Naltrexone, so i might also give that one a go as well.
  4. Its been 5 days now since I stopped taking all 3 meds, buspar, topomax, and lamotrigine. I would say by far buspar had the worst side effects - but after being on doses of these meds for 3 weeks, and stopping all of them at the same time, I'm more or less back to baseline. Topomax I would say is definitely not a cure on its own, but can be useful at aiding in dp/dr symptoms. What's nice is that the lowest dosage (25mg) has an immediate effect, and I don't believe topomax on its own had a tremendously negative impact on my hppd or baseline as the buspar did. I'm seeing my outpatient psych next tuesday to see what my options are. Might give keppra a go.
  5. Funny, I had to stop taking Lamotrigine as it was giving me ataxia. Loss of coordination in body movements, involuntary body movements etc. I'm wondering what the risk of developing Ataxia is with Depakote or Keppra?
  6. @Onemorestep although I can't find any information that directly mention Topomax's dopaminergic activity, I can only mention how my experience went, and can confirm among the various other people at the inpatient centre who were on Topomax had felt the same effect initially. It does stabilize after a while though. From what i've read about Keppra, Topomax and Keppra seem to have a similar initial onset, where one feels alert, full of energy etc, but similar to Keppra, Topomax's rush stabilizes over time. @TheMythos definitely not a placebo effect, topomax's effects can be felt immediately after you take your first dose, and at the smallest dose available. (25mg) It just aids your brain in the hear and now moment to sort of snap out of DP/DR. Visual acuity is improved, without having an effect on visual snow, and you feel clear headed for a while. Unfortunately in my case, it didn't take long for me to recognize the negative effects that Buspar was having on my visual snow, and at that point my doctor was really trying to push my dosage of Topomax, far too fast for me to handle in such a short time frame. This is inevitably what caused me to have to stop taking these meds and reset for a while. Does depakote carry a risk for Ataxia? I'm just getting myself back to baseline state before I start trying out some new medications, although keppra is definitely on my to do list at the moment.
  7. Perhaps maybe why some people have reported that taking more LSD with meditation has cured them etcetera etcetera.
  8. @Onemorestep any thoughts on this theory? If anything it would have been the buspar that actually caused the chain reaction to happen due to its excitation of the already neurotoxic 5ht2a. Its only after I've completely discontinued buspar that I've noticed lamotrigine have any effect on my hppd. It had never helped prior to me having taken the buspar or topomax. Sigh. I wish I could spend a whole life doing research on the subject. And help people in the same boat. But, it's almost serendipitous, that this would work.
  9. @justhere In hindsight maybe I wouldn't recommend taking buspar. I had negative side effects due to the fact that it excites the 5-ht2a receptor. Interestingly enough I've been on lamotrigine for a month prior to taking buspar, and have only noticed the lamotrigine starting to work after I took the buspar for about 3 weeks. After discontinuing buspar the lamotrigine started to work. It has taken about 4 or 5 days to recover from the effects of the buspar, and now my visual snow is starting to go away while I'm on lamotrigine.
  10. My only theory (and sad attempt at pharmacokinetics) is that part of the basis of action of LSD or HPPD is that certain neuroreceptors fold in on themselves. Thus not really being in a convulsive state. Perhaps the other medications I was on (which re-aggravated some of those neuroreceptors) caused them to temporarily open back up again just long enough for the lamotrigine to work its anti convulsant magic, not allowing those neuroreceptors in their re-aggravated state to fold back in on themselves.
  11. Either way, i'm going to continue to pursue treatment, for now with lamotrigine mono therapy for a couple of months. Il keep tabs on myself I suppose.
  12. I'm only speculating at this point, I can't help but wonder; i've been on lamotrigine for a little over a month, and just started taking it in the mornings. In my current overly stimulated and exacerbated state the lamotrigine is having a very positive side effect, visuals are decreased by like 50%, and my body calms itself right down from all the other meds I was on. It really sucks, but the lamotrigine is noticeably working now, something i've never noticed before. I can't help but wonder if there is a connection between that overly stimulated state, and the lamotrigine actually starting to become effective. Perhaps part of the reason why it works for some but not others? Not sure, and not going to say anything thats either here nor there. What makes me wonder now is if the lamotrigine will continue to work as it is after my symptoms return to baseline, or if it is just temporarily helping my overstimulated state. Im reluctant to say.
  13. Topomax is used in addiction/rehabilitation centers here as an aid for people who are going into post acute withdrawal from other drugs as it has an initial stimulant effect. The whole idea being that it's a pharmaceutical option to being able to viably provide people with a better chance of not relapsing.
  14. Yup. What I noticed with buspar was that if I took it alone it would make the visuals worse; interestingly enough being on a dosage of topomax was able to make the negative side effects of the buspar disappear while holding onto the good ones. Unfortunately my doc really wanted to push the dosage of topomax, and when the topomax ship hit the iceberg the whole thing got revealed. Topomax was doing a really good job at hiding everything that was going on and replacing it with a dopamine rush (think anticonvulsant, and your brains literal ability to block out allot of neuroreceptors you normally wouldnt and just bypass all of that, and think) What I'm not sure about is this, for the first two weeks I did feel great, I think what ultimately winded up happening was that I couldn't notice that buspar was having a negative consequences on my neurochemistry, and that the topomax was hiding it. After having a negative reaction on topomax everything flipped and started to come crashing down. I'tl probably be a week or two before I return to baseline, but interestingly enough in this really sort of 'exascerbated' state after stopping both other meds, I've continued to take lamotrigine. Interestingly enough I seem to notice a quaint positive side effect from taking the lamotrigine. I've only been on it for a month, and maybe it's only in this exacerbated state, but it absolutely helps with a certain level of my hppd's excitation right now.
  15. Ah. Guys I have to update this. Ever since I had a bad reaction to topomax at 200 mg it ruined the combination of these meds. I've never been able to regain my baseline again, after re taking topomax and buspar. I've stopped taking both completely, visuals are still flared up from my breakdown at 200mg. Luckily this all happened in under 3 weeks. If anyone does try this method, start out at the lowest dose of both meds. Stay on them for a full month, and then decide how you feel and if you'd like to keep taking them. I'm on a break right now and am just on 100 mg of lamotrigine.