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Hallucinogen Persisting Perception Disorder (HPPD) Support Forum

hope1

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  1. No. The research study is specific in trying to determine the underlying problem behind the disorder which the researcher believes might be reversible. There is no cure currently on the table but the research could lead to one. Could be soon, might be never; we’ll never know unless the work he’s doing is supported.
  2. Any thoughts on this medication as a possible means to ameliorate HPPD? How do these neurosteroid drugs relieve depression? The drugs are mildly sedating. They interact with GABA receptors in the brain. GABA is the major inhibitory neurotransmitter in the brains of all mammals, so an agent that augments GABA can be sedating. In fact, the biggest challenge with brexanalone for postpartum depression is the potential for excessive sedation. Sleepiness also affected some of the patients who took SAGE-217, but that's not necessarily bad because sleep disturbances are a big problem in depression and in a range of psychiatric illnesses. The drug may relieve depression at lower doses, without causing the sedation that was seen in some patients in the clinical trial, but that needs to be tested. https://m.medicalxpress.com/news/2019-11-neurosteroid-antidepressants-horizon.html
  3. Any thoughts on this medication as a possible means to ameliorate HPPD? How do these neurosteroid drugs relieve depression? The drugs are mildly sedating. They interact with GABA receptors in the brain. GABA is the major inhibitory neurotransmitter in the brains of all mammals, so an agent that augments GABA can be sedating. In fact, the biggest challenge with brexanalone for postpartum depression is the potential for excessive sedation. Sleepiness also affected some of the patients who took SAGE-217, but that's not necessarily bad because sleep disturbances are a big problem in depression and in a range of psychiatric illnesses. The drug may relieve depression at lower doses, without causing the sedation that was seen in some patients in the clinical trial, but that needs to be tested. https://m.medicalxpress.com/news/2019-11-neurosteroid-antidepressants-horizon.html
  4. Nobody gives a shit because HPPD is not part of any social or scientific dialogue especially coming from researchers like Nutt and Nichols who are actively engaged in psychedelic drug research. They won’t lift a fucking finger to do an FMRI much less ANYTHING else to help us!
  5. Neither of them give a damn about those of suffering with HPPD!
  6. @yosoydiego I’m curious who you work for; MAPS, Buckley, Heffter, etc?
  7. I had a close friend of mine try that approach. He said he was doing well for a while but ended up at a “rehab” center and has been there ever since.
  8. So what is an engineer doing lurking and supporting the work of Nichols and Nutt?
  9. There been research on this condition since the 1960’s. Dr. Henry Abraham spent four decades researching this disorder. Your suggestions are basically bullshit. Get out of the way, stop discouraging us while we take things to the next level. If Dr. McConnell didn’t think his research protocol wouldn’t reveal something, it wouldn’t be done.
  10. You don’t know that I’m fact unless you have a PhD attached to your name you don’t know anything. The dysregulation between excitory and inhibitory Interneurons is found in epilepsy as well as other neurotypical diseases like autism. It is theorized that the glutamate overload in psychedelics affects the neurocoherence of the brain in a similar manner. That’s the beauty of neurological disease; they each have their own flavor. Again, none of this matters without research being conducted. You are telling us to give up without even trying. Another pro psychedelic pawn trying to sweep as under the rug to make way for a for profit renaissance without any regard or plan to address anyone harmed by psychedelics. I’d kick your ass if ever we met you life life piece of shit.
  11. All of which are good questions but first an assessment of where the damage to the brain has occurred.
  12. In fact, according The the research protocol Dr. McConnell has drafted for HPPD, he believes this condition is reversible! This is not some quack but a distinguished Neuropsychiatrist who is working with PhD that are brilliant and want to help unlike Nutt and Nichols! They’d sooner write us all off instead of helping! Screw them!
  13. Name dropping guys like Nichols who gives a damn about us doesn’t score you any points here my friend. Research on this condition is anecdotal. No major attempt at fully elucidating this condition has EVER been performed. Dr. Harry McConnell is going to do what Nutt and Nichols refuse to because they’re all about legalizing psychedelics without any care or consequence should something go wrong as in HPPD!
  14. This not schizophrenia or psychosis. It is more akin to a drug induced form of acquired epilepsy due to glutamate overload from psychedelics...
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