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  1. 6 points
    You might have better luck on reddit at /hppd There are plenty of idiots there who also had some ultra mild hppd and want to believe that severe hppd is just a myth so they can carry on drug taking.
  2. 3 points
    Hi! My name is Madison and I've had HPPD for 1 year now. It has improved incredibly with the right medications and changes in lifestyle, but I still suffer from it everyday. I am a documentarian and animator and want to accurately depict the struggles and stories of people who deal with HPPD. I think the best way to depict the lives of those who have HPPD is through the eyes of someone who has it as well, instead of someone who may or may not sympathize with those who have HPPD. My goal is to spread awareness through personal anecdotes, poems, visual representation through animation, interview, and sound to make a documentary. I am seeking out a large variety of people-- those who were just diagnosed(or self diagnosed), those who are fully recovered, those who have had it for years, and those who are professionals/doctors/knowledgeable about HPPD. I have a close relationship with my doctor who worked under Dr. Henry Abraham so hopefully I could interview him as well.This project I expect to take over the span of 2-3 years. I really want to make it the best that it could be. If you are interested at all in making this happen, whether you are willing to be interviewed (even with your face blurred out to hide your identity), or if you want to share your writing/send audio of you reading it over, or any way that you feel like you can contribute would be fantastic. I am willing to travel far to capture footage (right now I am based in the east coast). Please either comment or message me if you are interested; our stories need to be told.
  3. 3 points
    Why don’t you take that article and shove it up your ass motherfucker? HPPD is a real condition and you have absolutely nothing worthwhile to say that will add value to our plight so pack up your shit and get the fuck out of here. There are people, kind, compassionate, caring individuals that are credentialed looking for solutions to solve HPPD. What you are doing, in effect, is discounting the severity and validity of this disorder by chalking it up to being in our heads. Buddy, I would relish the opportunity to switch places and to be frank, you wouldn’t last a day. Don’t you come here with your bullshit trying to deconstruct something that you clearly have no idea what the fuck you’re talking about, ok? Keep it moving, don’t ever come back, and learn both some manners and respect when you come to a support group like this scumbag.
  4. 3 points
    Consider this your final warning... Keep your theories to your own threads or you will be banned. I hate banning anyone, but your insistence that your opinion is fact is draining for everyone.
  5. 3 points
    Why is it that every thread that has some problems, you are involved? Here's some advice... Stop stating your opinion as fact. Stop belittling people who actually have hppd. You have your theory and we've allowed that opinion to stay on the forum in your threads... I don't want to see any more of it on other threads. On the OP... I think weed can give you hppd, and that is without thinking about laced weed or synthetics. The good news is that most everyone who has arrived here with hppd from weed has recovered quickly.
  6. 3 points
    Hey guys, just wanted to drop in and post an update on my HPPD recovery... In another six months I'll have my five year anniversary of when I first got HPPD. I've posted every year on that day and I plan on doing so again in six months but something just triggered me to want to post now. Basically I'm updating a lot of stuff on my computer and I went through old notes I made when I first got HPPD. I hadn't read them in three years. It was surreal to see how far I've come. So much of my notes were about how painful life was each day, how I could barely make it through, how HPPD was like hell and how I thought of suicide constantly. I also had severe depersonalization which I wouldn't wish on anybody. I literally couldn't tell whether I was alive or not when I first got it. It was really bad. Though I'm not fully healed and still have minor symptoms of HPPD (mostly visual snow, occasional tinnitus, some afterimages at night, etc.) I'm also at the place in my recovery where I'm able to move on with my life, and that's truly a miraculous thing to say considering where I was even two years ago. This point I've arrived at is all I ever wanted when I was living in a 24-7, Alice-In-Wonderland hellscape of a constant lowgrade acid trip. I would have given anything to be where I'm at today. And yet, here I am, and it doesn't seem so special because HPPD takes so many years to heal from. As many of you know this disease is not something that just disappears overnight. It takes many years of backbreaking work to improve, but I'm proof that if you're willing to put in the work you can get to that place. If I could impart any advice on those who are suffering right now and don't have much hope I'd really emphasize the power of natural healing. The body is a healing machine. It's designed to repair itself at all times. The main hindrance is of course interfering with this process by causing your body even more damage than it can handle and our modern world is essentially a barrage of micro and macro insults to this repair system. My true healing journey began when I put down the fast food, spent countless hours in nature and in sunlight, always kept my body moving, nourished myself with natural foods and medicinal plants, embraced the power of love and took steps to face my own personal demons and confront my childhood trauma that manifested in the anxiety that got me HPPD in the first place. If you're at all stuck or just wondering how you go about navigating a healing journey I really hope you'll consider getting back in touch with nature and letting evolution do what it's been doing for billions of years on this planet. I don't mean for this to sound too woo woo but I just know it works because I tried everything and natural medicine in combination with time is the only thing that gave me actual results. Please stay hopeful if you're able. I understand as much as anyone how distressing and hopeless this disease can be so I'm not gonna lecture anyone on how they should see things, but I do believe there's almost always reason for hope with anything, even this bastard condition. If anyone needs help or advice or just someone to talk to please don't hesitate to reach out. -- K.B.
  7. 3 points
    @TryingToHelp At first I was being diplomatic since I think everyone gets to have a second chance. But now I'll say it : Please fuck right off. You're just a troll and do not contribute anything to this forum. If it were for you, every single disorder is caused by anxiety. Yes I'll repeat it again, Fuck. Off.
  8. 3 points
  9. 3 points
  10. 3 points
    This is true of most diseases and disorders. Why don't you (and other members) let the doctors do the diagnosing - they are the ones who defined the disorder. Read more posts. Some have no anxiety. Some are actually glad to have the visual anomalies. I personally know one on the DPSelfHelp forum. You think you know all Native Americans? So your personal experience make you knowledgeable about everyone's personal experience? n=1 is a very small sample for statistics Clearly you are very impressionable. Perhaps you have learned to turn on or off HPPD at will. Patent that, you'll make millions and put the cartels out of business. Again, leave the diagnosing to the doctors It would be 'cool' if a little CBT would solve the problem. Read the posts. Plenty have tried CBT and other psychological techniques. You seem to be focused on your perceived reality. You need to respect other peoples experiences and not just your own. Nothing wrong with discussion anxiety and it's effects, etc. It is your manor of 'discussion' that provokes negative responses Please do. Dr A has published many papers regarding the long term aftereffects of LSD, etc. And these do not declare anxiety being the root of the problem.
  11. 3 points
    I was extremely ignorant to the possible side effects and long-term damage that could be obtained from the drug I took, especially the small dosage. I was carefree and inexperienced, being a huge noobie with drugs and looking for some sort of relief. Again, I don't care if you do not believe me but I know it's the truth and that's more than enough for me. You can't just go into a disorder forum and declare the disorder isn't real, expecting 0 argumentative responses. Maybe if you approached this with a better tone, you could've explained your theory without disregarding HPPD in its entirety.
  12. 3 points
  13. 3 points
    June 11, 2019 SUBJ: Faces of HPPD Survey/Research Published – RESULTS! Dear HPPD Online Community: As a mom with a grown son with HPPD, I was so fortunate to come across this forum several years ago for information and support. David Kozin, who runs this board, is an amazing man to have created and maintained this website and kept up his work/studies over the years – all the while suffering with HPPD. I would like to thank him for this platform, and well as thank those of you who participated in the survey that I launched four years ago to collect data about individuals who had received an official diagnosis of the disorder. Fast forward…. Here it is June 2019. Long overdue for the published report, however, I lingered – always hoping to gain a larger sample of subjects. I am fortunate to have a PhD in psychology, experience in research, and a heart to try to make a difference. Instead of publishing a book, it only made sense to get the results in the hands of the scientists and medical professionals through scientific writing. I am so happy to tell you… the peer-reviewed medical journal, Addictive Disorders & Their Treatment, published by Wolters Kluwer publishers, has reviewed and accepted my manuscript for publication in an upcoming issue. Last week the article completed rounds of publication editing and formatting. The article is posted at their website for advance release. Lewis, DM, Faces of HPPD: Hallucinogen Persisting Perception Disorder Patient Survey Results and a Descriptive Analysis of Patient Demographics, Medical Background, Drug Use History, Symptoms, and Treatments. Addictive Disorders and their Treatments. Forthcoming 2019. The link is here: https://journals.lww.com/addictiondisorders/Abstract/publishahead/FACES_OF_HPPD__Hallucinogen_Persisting_Perception.99733.aspx (NOTE: This direct link will change probably in a month or two when the article is given a print-issue date – right now, it is advance copy, undated. In the future, you can search the article at https://journals.lww.com/addictiondisorders/ . While the article is available for immediate download, many of you know that publishers charge money for copy downloads (this one is $49), and authors cannot give away their copy. This, I know, is not a good thing for some within the community who do not have the funds. However (here’s the good news 😉), I contacted the publisher and obtained permission to publish a summary of the results (the important data!) and I created an infographic that provides you all the results. I am including it here as a .pdf file, attached. It’s reader-friendly, and I hope it provides insight. I want to mention some findings that particularly concern me: the high rate of suicide ideation (among other co-morbid psychological/psychiatric symptoms reported), and the significant number of individuals who reported being unable to work due to HPPD. I feel strongly that HPPD needs recognition as potentially disabling – and I believe there are some individuals who may need government assistance (eg, Social Security Disability benefits). My future work leads me in the direction of carving a path for HPPD as a qualifying mental disorder for eligibility for assistance. I will keep you posted on that. Again, thank you so very much for those who partook in the survey. My best wishes to each of you for good health and peace of mind, Doreen M. Lewis, PhD https://www.facesofhppd.com https://www.vellichorresearch.com Faces of HPPD Infographic - LEWIS.pdf
  14. 3 points
    I was going to write an introduction, etc. I don't have the energy now, but I do think it is VERY important that people with HPPD learn the truth about the amount of information that has existed out in the academic literature and why it frankly pisses me off that some researchers see that since 1969 there has been a stable disorder of symptoms that account for our condition, but they ignore it or don't have the time or desire to invest in researching what came before. I have read over 100 articles for my undergraduate thesis, and luckily had access to all of the databases I needed. So, I was privileged . Ii want to share that with you. I want to do these in videos, but I haven't set that up yet. So, here is the first major paper on HPPD that literally covers every major point and gets it right: Copy of horowitz_flashbacks (1).pdfCopy of horowitz_flashbacks (1).pdf
  15. 3 points
    This is a good list. I am setting up the space where people with HPPD, their allies or medical professionals can use to look up information about the big questions: What pharmacological treatments have evidenced based positive results? What medications are specifically CONTRAINDICATED for individuals with HPPD? The page would have 30 or so medications I would imagine. It could be broken down into a Professional and a Consumer Page. I think it would be nice if a more advanced write up with citations were included as a Continuing Medication Education "type" certification, which a licensed medical professional can take in order to be listed on the World Map with their information as a doctor that at minimum has familiarity with the most important concepts.| The goal of the web site is to create the most value and impact with the little money that we have. If individuals with HPPD go to one of these doctors, and the doctor does not prescribe risperidone as a first line of defense because the web site details a very outspoken research and patient community about why this class of anti-psychotics will produce an increase in symptoms. Imagine saving 5 people from having to experience this awful period, which I have known some people to have been hospitalized and placed on anti-psychotics, and as the symptoms got worse they prescribed more antipsychotics. It was about 6 months or maybe a year later, the medication was stopped and the symptoms were dramatically improved. This is where everyone can have an impact.
  16. 3 points
    muh "MMS CuReS EvErYThiNg" Stop shilling for KNOWN TOXIC compound, I suggest anyone interested in MMS watch this. (inb4 dosage matters) To anyone reading this, If you want placebo effect, there are much better options out there. I know (from personal experience) that one gets desperate to find cures, but MMS definitely isn't what you are looking for.
  17. 3 points
    So it's been six years and I've managed to get the non profit created and the first major study on hppd underway. We are looking at the beginning of 2019 to get the study going. In the interim I've worked rather intensely in raising awareness of hppd on social media. Word is getting around about this horrible condition especially among the pro psychedelic reseaarch community who sadly have shown the greatest resistance in accepting the validity of it and willingness to help. Our study may prompt them to rethink their position
  18. 3 points
    Here is my success story. I really hope this helps people because when I first got HPPD almost 4 years ago at age 23 I was a total train wreck and thought I would never get my life back. I am certain that this forum played a huge role in saving my life because for a long time I was seriously worried that I would have no other way out than to take my own life. This was definitely my darkest time and it makes me a little sick to think about it but I feel like I owe it to all the kids out there who are suffering. I'll get to the point. I took mushrooms for the first time ever and I flipped out. There seems to be a pretty standard story to this...total fear, a feeling that the trip will never end, it was a feeling I had never felt before. In my mind, I went to hell if it does exist. I woke up the next day feeling wierd, just off, sort of empty. I didnt think it anything serious until a week later, on new years day, I woke up after a night of partying in Las Vegas, and I knew something was wrong, I was sick, I was throwing up, and I was terrified, my vision was changing before my very eyes, everything was moving, and I knew something was wrong, the first thing I thought when I got up...the mushrooms were coming back to get me. I tried to tell myself it would be ok, that I was just sick from drinking, but it didn't stop. I didn't eat for almost a week, and I went to the hospital to get an I.V. to rehydrate me. In the ER, there was a true psychotic woman having an episode, It terrified me, because I felt I could somehow relate to her. I thought I had really lost it and I would never be the same. I'd heard of people "freaking out" and stories from the 60s, musicians like Brian Wilson going nuts on acid ect. and I starting thinking I was one of them now. I went home and felt so empty, but I couldn't even cry. My parents came back from a trip they were on, and it was like I didn't even know them, I was in my own little world. Things that were familiar were foreign to me, nothing was the same. As I worried more, things got worse, I started having panic attacks daily, I couldn't sleep, and my visual symptoms got worse. I had horrible headaches, nausea, paranoia, depression, visuals, the whole nine yards. At this point I think i was pre depersonalized, the panic was very strong, and it drove me deeper into a state of numbness. I was having terrible nightmares when I did sleep, finally, I think my mental anguish drove me into a state of numbness, where I couldn't feel anything around me, just like a zombie. I would say this was about 4-6 months into it. I started seeing therapists, and it helped a bit to have someone I could talk to because I didnt have anyone. None of my friends got it, and I was scared to tell my parents. At that point I wasn't even sure if they were real. I started reading on the forums, and this was a real game changer. I started to learn about some of the things that were happening, like the depersonalization/derealization, anxiety, ect. But more than that, I learned that there were people just like me, that I could talk to and would understand me, and even better that some people had survived it. This gave me what I needed, a little hope. Something to AIM for, a light at the end of the tunnel. Of course I was unsure and skeptical that I would get better, but at this point, in what seems like a rather odd reasoning, I decided that I couldn't be any worse off, and that the only choice I had was to get better, I really had nothing to lose. I knew it wouldn't happen soon but I thought, hell, I've survived this long (it was probably a year in) I can keep going, so I kinda just put my life on autopilot. I bought myself some time, I said, hey I'm just gonna deal with this day to day, not try to push myself too hard, and maybe in a few years I'll at least be able to function. That was a big deal, I accepted my situation, that it was gonna suck now, and that it would be a long time before I got better. During this time I had a lot of bad days, I also had some good ones. But every time that I had a good day, I kinda put that in my mental bank. Like saving pennies at a time. They add up. I made habit of doing things that would promote overall well being. That meant regular exercise programs, eating better, meditation, and yoga. I began to make steady improvements, I started having more good days, and things looked better for me. Someone once described HPPD as sort of like throwing a stone into the water, a huge splash, then lots of waves, ups and downs, and the slowly get less and less intense and I would totally agree. There was a long period of about 1 1/2- 3 years into HPPD that I began to get frustrated because I would feel great and think I finally beat it, then relapse again, I just wanted to be better, but again, time heals. This coming New Years day will be my 4 year anniversary of the day HPPD and I can say that this is behind me. In fact, I look back on it and I almost don't believe myself. It's almost like it was just a terrible nightmare. Which is how I had hoped I would look back on it some day. I want to put it behind me and never look back. But at the same time I want to help the kids that are on here because I know how terrible they feel and they need help just like I did. I owe it to someone because I survived and I want people to know that you can beat it but it takes work and commitment. I still feel a little lost, like I'm not sure who I am as a person, but I at least feel like I know where I am (haha). I just spent 4 years in a nightmare and now I'm awake. So I will try to offer some advice. The forums are great for helping you out, but don't spend too much time here. Don't spend hours on hours reading about peoples problems, about mental disorders. Education is good but at some point it will only make you more obsessive. Also, there is a lot of negativity here that will bring you down, because people that are on here are mostly here because they are having problems, not because they are doing great. For every 1 success story you will read about 20 horror stories. It's like watching the news, they only report on the bad stuff, you will never turn it on and have the reporter say "hey, everything is great." Again, do stuff that promotes good health, a healthy body is a healthy mind. Get outside and enjoy nature. I found it easier to connect with natural objects. Try to feel the sun, or the breeze on your face, little things like that. They can help you feel alive. Stop doing drugs, alcohol, tobacco, or limit your intake if you can. Smoking weed really made things worse for me. Talk to someone that can offer something positive and will understand your situation. If anyone ever wants to talk, on the phone, email, whatever, hit me up. Believe you can get better.
  19. 2 points
    Hello everyone! Hope everyone is doing well. Been wanting to make a post for months now but just haven't been able to find time. The main reasons for my post is to share my progress and share what my methods were for the progress in hopes that others can possibly benefit from the same treatments. With very little notoriety and/or profit for medical science HPPD gets very little to no coverage at all, so I hope this is something to help those who are destitute in this insufferable and most terrible disorder and condition which could be described by none other than the manifestation of hell itself. To start I just want to explain that at the beginning of my condition I could scarcely drink 1/4 - 1/2 a cup of 12 oz coffee, I would often just discard the rest, anything more would initiate massive anxiety and increases in other symptoms involved with HPPD. Now, however, things have changed! I didn't really have much progress after about a year, things stayed relatively the same. I would, however, like to share a photo of how much caffeine I can consume, and explain how much I do consume daily, as a proof of improvement, that I do attribute to a various degree of long term treatment that is available to everyone. [ Here you can see the maximum amount of caffeine that I can now consume daily if I choose, it will give me minor amounts of anxiety, but its not beyond what I can handle, where before I could come nothing close to this. Don't be confused either, the coke I can drink whole as well, and the coffee thermos is 24 oz.. This is no where near what I was capable of consuming before, and took about 2-3 years to accomplish. On average daily since this is a bit much for me, I only drink the 24oz coffee, which I make every morning, coupled with a few supplements that have a mild stimulant effect. I've even been able to take minor amounts of stimulants that I always enjoyed before my condition(all legal of course). Its been a long road. So, here I will share two herbs that may potentially help you, I don't claim that it will resolve all your symptoms all together, I do still have issues, but they are significantly decreased from what they were. I do believe that this is a neurological disorder, but I atop the two herbs to share in potentially assisting the progression of the suffering from this disease, I do also have a possible alternative to the diagnosis to this disorder after researching very significantly microbiology for other reasons not involved with HPPD. Tomorrow in my next post I will explain the two herbs, I want to elaborate more so on the other possible diagnosis involving microbiology which is a possibility and will tie in to the treatment for both possibilities involved which I think everyone will be somewhat intrigued about. I hope everyone the best and hope you're all hanging in there and doing your research trying to improve this condition. Tomorrow I will post more and for sure elaborate on this condition and the possible treatments. I would like to shout out to Jay, Hope, Kozin, dayum_son, and a few others too but its been a while and I'll have to look up the screen names. Sorry for anyone that has PM'd me and I haven't responded I haven't been on for a while but I will try to be on more. I also wanted to post old information which is basically a sum up of my old post that I typed up for someone in an email which will save me a lot of time than typing it again. In my next post I will make an alternative possible diagnosis that is far different from the foregoing. I want everyone to know too that you're the greatest even if everyone abandons and leaves you in your suffering. Keep fighting to save yourself and bare your infirmities with this terrible disease and I hope anyone that leaves or abandons you adjourns their due justice in the universal law of karma to the fullest extent and then some if God so feels it. I hope too that you're all relieved of this curse that destroys lives and that people will supplicate to the suffering of the nightmare that we live waking. I hope to help you all in the next post. My heart goes out to everyone with this condition. Stay strong. The actual etiology, though often argued, is most likely to be a form of excitotoxic apoptosis following glutamate receptor overstimulation. It could also include variable causes including neuronal hyperthermia due to the overstimulation. This is commonly neglected as a possibility in health, research, and media, due to the fact that in MRI studies of HPPD sufferers and hallucinogenic users there is no "notable" damage that can be perceived. However I was able to accumulate quite a lot of MRIs from actual HPPD sufferers and there is a decent yield for white matter hyperintensities, enough to be suspect for possible neuronal degeneration. The white matter lesions also appear to be long standing ruling out temporary axonal demyelination. Another point to be shown that it neuronal loss should not be ruled out is the obvious fact that MRIs are only subject to detecting larger unscattered masses of neuronal lost such as that found in blunt trauma victims and stroke victims etc, but unbeknownst to your average physician its incapable of showing minute scattered neuronal loss which can be seen in the link of this lithium overdose patent. Case Report A 45-year-old Mr. S presented with a history of altered sensorium for the past 2 days. The patient had a history of five episodes of mania and two episodes of depression in the last 15 years. Six weeks ago he had an episode of mania, for which he was treated at a tertiary care center as inpatient and given a tablet each of olanzapine 20 mg, lithium 900 mg, and chlorpromazine 300 mg daily. A week after he was discharged from the center, while still on regular medication, he developed coarse tremors affecting the whole body and was unable to walk. When he was brought to the Accident and Emergency Department of our hospital, he was afebrile and was not responding to painful commands. His pulse rate was 105/min with exaggerated deep tendon reflexes. His investigations showed a raised serum lithium level of 3.9 mEq/L, creatinine of 1.8 mg/dl, and raised white blood cells of 24,800/μl. His liver function tests and sugar level were within the normal range. All his previous medications, including lithium were stopped, and he was treated with intravenous (IV) normal saline, IV ceftriaxone 2 g, and vancomycin 500 mg twice a day for 2 weeks. In order to rule out any infection, his blood was sent for culture, and a cerebrospinal fluid (CSF) analysis was done to rule out any neuro-infection. However, both blood culture and CSF results were found to be normal. A magnetic resonance imaging (MRI) of the brain showed T2 and flair hyperintensities in the bilateral parietal lobe and periventricular white matter changes, both suggestive of lithium toxicity [Figure 1]a. In view of his low Glasgow coma scale (8/15), the patient was intubated. Also, because of the severe lithium toxicity, hemodialysis was started. After two cycles of hemodialysis, the patient started responding to painful commands. His serum lithium level fell to 1.8 mEq/L. He was extubated on day 5 of admission. From day 6 onward, he started responding to oral commands, even though his speech was slurred. However, he had coarse tremors, truncal ataxia, and difficulty in deglutition. Subsequently, the patient was shifted to the psychiatry ward of our hospital for further management and for observation of manic symptoms. Physiotherapy was started, and within 2 weeks of intensive physiotherapy the patient started walking with support. His speech too improved. After 3 weeks, when his blood serum lithium level fell to 0.2 mEq/L, he started showing symptoms of mania. He was then treated with oral quetiapine, which was gradually increased to 300 mg/day. Thirty-six days after the first MRI, a second MRI was done. The second MRI showed up to 40% reduction in periventricular white matter hyperintensities in the bilateral parietal lobes [Figure 1]b. Even after about 6 months of follow-up the patient continues to have coarse tremors, dysarthria, and significant limb ataxia. Brain MRI showing hyperintensities.  So even after 6 months he was showing symptoms, which clearly demonstrates damage to the neural tissue. A clear example that MRIs are not completely effective and accurate in diagnosing neuronal loss. There are countless examples that be given to prove this, another is even in epileptic patients who are taking anticonvulsant medications as treatment, proven neurotoxic compounds, MRIs will only show neuronal loss after 10-20 years and will only show it as encephalopathy. So media and medicine claiming that this hallucinogenic compound are "safe" are ignoring a LOT of information. Heres just one of many abstracts that show through the study of MDMA that activation of 5ht2a receptions(those activated in hallucinogens) are neurotoxic Abstract 3,4-Methylenedioxymethamphetamine (MDMA or "Ecstasy") and 2,5-dimethoxy-4-iodoamphetamine hydrochloride (DOI) are hallucinogenic amphetamines with addictive properties. The hippocampus is involved in learning and memory and seems particularly vulnerable to amphetamine's neurotoxicity. We evaluated the neurotoxicity of DOI and MDMA in primary neuronal cultures of hippocampus obtained from Wistar rat embryos (E-17 to E-19). Mature neurons after 10 days in culture were exposed for 24 or 48 h either to MDMA (100-800 μM) or DOI (10-100 μM). Both the lactate dehydrogenase (LDH) release and the tetrazolium-based (MTT) assays revealed a concentration- and time-dependent neuronal death and mitochondrial dysfunction after exposure to both drugs. Both drugs promoted a significant increase in caspase-8 and caspase-3 activities. At concentrations that produced similar levels of neuronal death, DOI promoted a higher increase in the activity of both caspases than MDMA. In the mitochondrial fraction of neurons exposed 24h to DOI or MDMA, we found a significant increase in the 67 kDa band of apoptosis inducing factor (AIF) by Western blot. Moreover, 24h exposure to DOI promoted an increase in cytochrome c in the cytoplasmatic fraction of neurons. Pre-treatment with an antibody raised against the 5-HT(2A)-receptor (an irreversible antagonist) greatly attenuated neuronal death promoted by 48 h exposure to DOI or MDMA. In conclusion, hallucinogenic amphetamines promoted programmed neuronal death involving both the mitochondria machinery and the extrinsic cell death key regulators. Death was dependent, at least in part, on the stimulation of the 5-HT(2A)-receptors. https://www.ncbi.nlm.nih.gov/pubmed/22983118 Risperodone is a good case too for showing excitotoxic damage, a 5ht2a inverse agonist, and other anti convulsion medications which are 5ht2a antagonists there is a correlation with palinopsia. Palinopsia being obviously common with HPPD, the most probable reason being, that the 5ht2a specific neurons that underwent glutamate excitotoxic apoptosis, are now gone, and therein laying a lack of 5ht2a input, which would be similar to that of these drugs, being inverse agonists and antagonists. So this gives even more credence that HPPD is caused by 5ht2a induced glutamate excitotoxic apoptosis. So unfortunately for these sufferers is most likely that their diagnosis is neuronal loss. A sad day for anyone regardless if they are a drug addict or a one times user. Heres a study that shows the areas likely to be affected Brain imaging studies Until recently, many neural circuit models were based on animal studies, and implications for the effects of hallucinogenic drugs or disease models in humans were based on inferences from these studies. However, functional neuroimaging studies enable one to examine these neural circuit models directly and test specific hypotheses about the role of specific neural systems in the expression of ASC. PET with the radiotracer 18F-fluorodcoxyglucose (18FDG) was used to assess drug-induced changes in the regional cerebral metabolic rate of glucose (CMRglu), as an index of cerebral activity. We found that a hallucinogenic dose of racemic ketamine increased neuronal activity in the prefrontal cortex (hyperfrontality) and associated limbic regions, as well as in striatal and thalamic structures in healthy volunteers, giving the first evidence that functional alterations in CSTC loops may underlie the symptomatology of drug-induced ASC.50 This hyperfrontality finding was corroborated and extended in subsequent studies in healthy volunteers in which the effects of hallucinogens and NMDA antagonists including psilocybin, racemic ketamine, and S-ketamine were compared. In particular, we found that, despite different primary mechanisms of action, the two classes of drugs produced strikingly similar brain activation patterns as indexed by normalized CMRglu. Both psilocybin and ketamine markedly increased brain activity bilaterally in the frontomedial and frontolateral cortex, including the anterior cingulate. Lesser increases were found in the temporomedial, superior, and inferior parietal cortices, striatum, and thalamus. Decreases were found in the left caudate nucleus, bilaterally in the ventral striatum, occipital lobe, and visual pathway.9-11 A correlational analysis revealed that the metabolic hyperfrontality in ketamine and psilocybin subjects was associated with a depersonalization/derealization syndrome, thought disturbances, and mania-like symptoms.9-11 The hyperfrontality finding in ASC was further supported by evidence from brain imaging studies with ketamine and psilocybin in healthy volunteers27,51 and was also found in subjects treated with the classic pheny le thyl amine hallucinogen mescaline.52 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181663/ Prognosis is typically really bad with little recovery in patients that have extensive damage. Mainly the only saving grace is synaptic hyper plasticity. If you then take in to account the possibility for future advancements in neurogenesis and stem cell research there is some hope but there is the unfortunate case that regeneration of damage to the white matter shown in Axolotl Salamanders is structural deficient when taken in to account long distance axonal tracts. The Axolotl being capable to regenerating neurons sadly only can fill the area of these damaged long tracts with short neurons typically found in gray matter, making structural integrity likely deficient in functional regrowth. So even with neurogenesis prognosis is likely grim for these patients. There is a certain drug that I found that ends the cascade event of hallucinations right at the core of the matter and would in the event of a "bad trip" save these patients a great deal of permanent neuronal loss if they made it to the ER in time. I cant find the drug at the moment and I don't have time to find it but I believe it was simply an reverse 5htp2a receptor agonist. I was actually able to find some treatments in extremely old medical books too, which lead me to believe that the physicians were actually stimulating neurogenesis in their patients, but still even with that recovery is limited due to axonal tracts being lost in white matter, but it would certainly improve their lives. Instead of educating people of these dangers they promote hallucinogens as potential for all kinds of treatments and ignore negative effects. One study showed in 400 people who were given hallucinogens 157 report long term effects that did not resolve, some committed suicide. Heres the axolotl research The axolotl can regenerate multiple organs, including the brain. It remains, however, unclear whether neuronal diversity, intricate tissue architecture, and axonal connectivity can be regenerated; yet, this is critical for recovery of function and a central aim of cell replacement strategies in the mammalian central nervous system. Here, we demonstrate that, upon mechanical injury to the adult pallium, axolotls can regenerate several of the populations of neurons present before injury. Notably, regenerated neurons acquire functional electrophysiological traits and respond appropriately to afferent inputs. Despite the ability to regenerate specific, molecularly-defined neuronal subtypes, we also uncovered previously unappreciated limitations by showing that newborn neurons organize within altered tissue architecture and fail to re-establish the long-distance axonal tracts and circuit physiology present before injury. The data provide a direct demonstration that diverse, electrophysiologically functional neurons can be regenerated in axolotls, but challenge prior assumptions of functional brain repair in regenerative species. https://doi.org/10.7554/eLife.13998.001 This how complex the tracts are Interneurons a possibility, Dr. Abraham comments on this LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex. Marek GJ1, Aghajanian GK. Author information Abstract Correlations between 5-hydroxytryptamine (5-HT) receptor binding affinities and human hallucinogenic potency have suggested that 5-HT2 receptors mediate the hallucinogenic effects of lysergic acid diethylamide (LSD) and phenethylamine hallucinogens. Electrophysiological studies have suggested that a subpopulation of gamma-aminobutyric acid (GABA)ergic interneurons in layer III of the rat piriform cortex are excited by serotonin (5-HT) via 5-HT2A receptors. These interneurons have inhibitory inputs on pyramidal cells in layer II. In the present study, we tested low concentrations of both LSD (3-100 nM) and the phenethylamine hallucinogen 1-(2,5-dimethoxy-4-iodophenyl-2-aminopropane (DOI; 0.3-10 microM) on rat piriform cortical interneurons that were excited by 5-HT. Both LSD (3-100 nM) and DOI (0.3-10 microM) excited almost every cell excited by 5-HT. The maximal excitation achieved with LSD and DOI was 39% and 55% of the effect of a near-maximal 5-HT concentration (100 microM). Consistent with a partial agonist action, LSD and DOI blocked the 5-HT excitation of piriform cortical interneurons only at the higher hallucinogen concentrations tested. A specific 5-HT2A receptor antagonist, MDL 100,907, blocked excitation of these interneurons by 5-HT, LSD and DOI, but not by norepinephrine or alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate. Again, consistent with a partial agonist action of the hallucinogens, intracellular experiments showed that a maximal concentration of DOI (10 microM) induced fewer postsynaptic inhibitory currents than did 5-HT (100 microM) in pyramidal neurons in layer II of the piriform cortex. Based on the present electrophysiological studies, we conclude that LSD and DOI, a phenethylamine hallucinogen, act as highly potent partial agonists at cortical 5-HT2A receptors.
  20. 2 points
    I get eye floaters only when looking outside or very bright rooms, though I do not associate my floaters with my HPPD/Visual Snow Syndrome because I’ve always had them. Quitting marijuana causes anxiety and many bizarre withdrawal symptoms. After 40 days that should have began diminishing dramatically. I’d say you’d have noticed these symptoms during the early stages of marijuana withdrawal and are looking for them more, which in turn is creating further anxiety and exaggerating common disturbances that have always been there. Floaters are fairly common, especially with age. Go get your eyes checked and triple check your eyes are in healthy order, I’m sure they’re fine. Once you have received this confirmation, move on and live your life. with your mind clearer than ever since since quitting marijuana, you’re essentially in a new reality to what you’ve grown accustomed to. Enjoy your new sobriety and embrace being clean, well done and keep it up. It is not uncommon for those who have quit marijuana to experience increase in anxiety. with regards to REM cycles ect - I don’t think that’s linked to HPPD, as HPPD is mostly visual. Vivid dreams are linked to withdrawal symptoms. I’d say your dreaming more vividly because you no longer have marijuana aiding your sleep. Id assume this would diminish if you made yourself tired during the day with exercise and a strict sleeping pattern. My VSS/HPPD worsens the more I read into it and freak myself out - so if I were you, I’d just move on and focus on your drug recovery. This post is purely my opinion and if you are worried, seek assistance from a professional rather than me, who is purely giving you advise based on my experience and knowledge.
  21. 2 points
    I have been taking 1500mg Taurine steadily for 3 or 4 days now i was also taking 150 mg Valerian for sleep before bed and combined with the Magnesium supplement my symptoms seem to be gone (cured) all that is left is the thoughts.I was also trying to get the daily Choline recommended intake but i have doubt that had anything to do with it. Seems that trazodon was only making my recovery slower and hindering it. Update:after separating the meds i think the valerian is the more helpful one. i might also combine it with Melissa Officianis as the article mentions combining them is more effective in normalizing levels. Currently if i stop the med i get symptoms but they are reduced from what they were originally(unbearable)
  22. 2 points
    This magnificent disorder has been introduced to me around the end of 2017. I took throughout my "psychonaut" part of life 4-5 tabs of LSD. These didn't trigger any HPPD. The disorder kicked in once I started microdosing. I have probably microdosed around 5 times, not more than once per week. Now, we could debate about how bad it was for my brain to microdose but the real issue was the weed + microdose mix. Since microdosing boosts your brain to unimaginable levels (I have ADHD as well), it was difficult to sleep each day I'd microdose. To ease myself into sleep, I'd smoke a joint, usually from a strain that was 15-20% THC. After 2-3 microdose + weed mixes, I started to notice Visual Snow and small tracers when under the effect of THC. I thought it was cool and part of the microdose, didn't think much about it. Between the 4th and 5th microdose, I noticed that the Visual Snow and tracers would not go away, they would be there 24/7. Again, didn't think much of it since, well, I was taking many drugs, partying, and quite often. Last microdose, the visuals (no THC involved yet) started to freak me out and thought they just could not be normal since the dose of LSD I was ingesting was under the threshold dosage. But because I was an idiot back then, I still smoked the usual joint in the evening after the microdose. Visual Snow was VERY strong, it was broadband and pulsating as well. Since that day, I decided to stay sober. But the visuals stayed. The symptoms at first worsened, partly because the visuals were getting objectively worse, partly because I was obviously obsessing over them. Then they have stabilized and never really changed in intensity, maybe slightly worse for some visuals and slightly better for others. So what's going on with my vision as of today ? After-images, VS, bad night vision (well, bad daytime vision as well 😂), tracers though not very noticeable, among the other typical HPPD visual symptoms. The one that appeared much later than the other ones is what I'd call bouncy vision. It only happens when I'm calmly sitting reading a book or looking at my computer screen, suddenly my vision would bounce up and down rapidly just as if my eyes were looking up and down uncontrollably. Visuals aside, how's it going psychologically wise ? Not too bad. Mind you, I never had huge anxiety or DP/DR, only mild anxiety during the first year or so. It took a good year to stop obsessing over the whole story and to get (partially) rid of the guilt. I still think about HPPD all day every day and will probably for the rest of my life since the visuals are distracting. I consider myself lucky since I view my HPPD as pretty mild compared to reports from other members on this forum. I am also very resistant psychologically. I do not plan to seek medical help, doctors here usually just want to make a profit off the drugs they prescribe and do not really care about the patient's well being. I'm pretty sure most of the members here can relate to this. I have to confess, I did use a moderate amount of drugs even when affected by HPPD, and I have to say, it usually comes back to baseline after a few days. Still, not a reason to abuse drugs or alcohol. So what's next ? Party only a few times a year, no drugs except alcohol and cigarettes when out partying, get a reasonable amount of sleep, and go for a jog every now and then. I will look for a new job since the company I work for is making me go crazy and this actually increases my symptoms. Recently redeveloped OCD and hardcore ADHD because of the stress I endure in this place. The OCD + ADHD symptoms sort of vanished a few years ago but are now back stronger than ever. I should also start looking for a girlfriend since I spend most of my time alone. Even though I like this way of life, I realized it cannot be a good way to carry on with stuff. There's still a long way to go, but I believe that with some good will as well as with future experiences in life, things can only go for the better. Even if one day the disorder leaves my brain, I will always stand beside this wonderful community that, quite frankly, didn't deserve all of this. I wouldn't wish HPPD to anyone, even on my worst enemies. I wish everyone the best. Never give up ! P.S.: English is not my mother tongue and it's currently almost 3AM here, so do not mind ze somtims wierd inglish :p.
  23. 2 points
    Be patient. Healing can take a long time and the severity of visuals can vary from day to day. You're not taking drugs now. That's the single most important thing you can do. As the last post suggests, focus on trying to get your anxiety under control. I realize that's easier said than done. I find that exercise is one of the best ways to deal with stress. I've also found meditation to be very helpful. Don't stress because a month has gone by with no improvement. It takes time. Hang in there.
  24. 2 points
    25 years in June! What a morbid milestone! Just remember those first months and years (hopefully you don't get into the years part though) are always the toughest. Keep on fighting, Jay.
  25. 2 points
    Primary visuals. That and the "alien thinking" that countless doses burned into my skull. Neil Young wrote a lyric that is appropriate. "Like visitors from space, it's hard to find a place, to blend in and go unrecognized".
  26. 2 points
    Important Please Read: I've been reading a lot and I think that there may be a possibility and link to a nutritional deficiency in HPPD, which realistically would assess the strange variable nature of this condition. If you at immediate glance question the severity of nutritional deficiencies just look up Pellagra and Scurvy, they eventually die if its not corrected. Most vitamins are antioxidants and neutralize free radicals, and hallucinogens stimulate neuronal metabolism leading to excess free radicals. When free radicals are excessive and deficiencies have occurred of said nutrients, the free radicals can no longer be controlled and spiral out of control, damaging surrounding tissues. These tissues in turn become inflamed and even due to their neuronal nature start becoming demyelinated, this is the explanation for the very mild incidence rate of white matter hyperintensities in HPPD MRIs, however not in all. These demyelinations under the given uncorrected circumstances cannot or very difficulty be repaired, unless the deficiency is corrected. The deficiency would also explain why some people never get HPPD, even with extreme doses of LSD use, they have plenty of reserves of the free radical neutralizing vitamin necessary. It would also explain why some people only get it after multiple uses of hallucinogens, eventually they deplete the vitamin, whichever it may be. It would also explain the relationship with alcohol initiating HPPD in people who did hallucinogens a month or two beforehand, alcohol also may variably deplete the vitamin. It also could explain the spontaneous recovery of some few individuals that have reported it. It would also explain why multiple different drugs initiate HPPD, from alcohol, to weed, to hallucinogens, they all stimulate neuronal metabolism by excitation and or drain certain vitamins that are vital to neuronal functioning and maintenance, hence the symptoms. Also some of these vitamins are absolutely crucial to proper neuronal function and a deficiency only of some, like Vitamin B3 can lead to psychosis. I could elaborate further on this but will refrain for the sake of brevity. If anyone in the slightest bit thinks this to be a complete impossibility, like i said look up pellagra and the mental health issues they have, and even vitamin b12 deficiencies cause demyelination of axons. And even some may argue that the nutritional RDA is met by common foods, this assuredly isn't true, and proven not to be true, especially in the cases of drug use and alcoholism, there are definitely related deficiencies common with these habits. I think that this possibility has some of the most merit than any of my other ideas, so if anyone would like to try and experiment as to whether a treatment will work, then they should get a full spectrum b vitamin complex(All B-vitamins known). and also Vitamin C. The B complex should be higher than the average listed RDA, as typically it wouldn't be enough. And the vitamin C needs to be at the very least 1000mg a day. Treatment should be carried out for 6 months. I wont get in to all the details as to everything correlative with vitamins, their deficiencies, and their importance, but if anyone cares to know more, they can read "How to Feel Better and Live Longer" by Linus Pauling, two time Nobel Prize winner and profession chemist. Even if the treatments don't work, at the very least it will certainly improve the health of the person taking these vitamins. If its not that then we may have some genetic defect. If you do try this treatment please report that you are trying it, and also please absolutely follow up with your results in the future. Thank you! Edit: I also forgot to add that I read that taking large doses of vitamin B3 will end an LSD trip within roughly 30 minutes, which shows a specific relationship with it and hallucinations, but not however with LSD diectly as far as I can conjecture, as LSD usually is metabolized within 30 minutes of hitting the blood stream. However the hallucinations continue for hours, which shows that the actual cause of hallucinations are downstream from LSD metabolism, and have a direct correlation with Niacin(b3) if thats true. I didn't read it from what I would consider an absolute reliable source, but there very well may be some merit and truth to the statement, as it wasn't an unreputable source either. If anyone else knows more feel free to share.
  27. 2 points
    This is what your argument actually looks like to @TryingToHelp
  28. 2 points
    Wow. There is no excuse for being mean. If someone posts a link you don't agree with, perhaps you could help them understand why you disagree with the article. We don't want people to stop sharing information because it doesn't meet some intellectual hurdle. If you disagree, explain why instead of taking a virtual swipe at someone. We're here to help one another, cutting people down doesn't accomplish that.
  29. 2 points
    Look at all the other posts, no one else is giving some definitive diagnosis. We just offer our opinion and advice... No one is telling him/her that they definitely have hppd and to jump on x,y,z medication. Literally all you need to do is say something like "hey, my personal opinion is that you can't get hppd from weed, but I do have some suggestions on coping with the anxiety"..... That's it, all you need to do to help someone, while not coming across as a know all. The problem with having this binary mindset is you can also cause damage... Now, imagine this guy actually does have hppd, but takes your diagnosis as gospel and thinks, "ok, I don't have hppd, so that means I can try SSRIs, a common anti anxiety med"... They take that and fuck their hppd even more. Dangerous, right? Leave the diagnosis to the doctors... This place is to offer personal advice, opinion, and non binary thought about the causes of hppd (no one is right or wrong, it is just info and advice).
  30. 2 points
    Have you actually read them? I don't think you have, otherwise you wouldn't be saying that. At this point you must be literally insane. The majority of posts claim: Not full recovery Significant recovery, but lingering symptoms that do not appear to be resolving Accepting said symptoms as a new part of life Using various medications and supplements(physiological) Relapses in symptoms Most of the responses claim consistent prognosis of HPPD Most do not claim using ANY type of mental therapy The few that do are typically for things unrelated to HPPD and usually for past emotional trauma Are you aware that the body has natural healing capabilities, that have nothing to do with the mind? If there are even any cases of complete recovery with using ONLY mental therapy in that thread, which I was unable to find, they will likely account for 1 to 100 posts, if that, which is a 1% recovery rate, which means in medicine, its not a cure, it doesn't work, and you're an imbecile. You are by far one of the dumbest most ignorant and persistently stubborn people I have ever seen, not only have you been proven wrong multiple times with massive amounts of evidence, but you fail to actually provide any solid evidence what so ever, your theory has no real theoretical foundation even, most mental health conditions and their etiology also prove you wrong, as schizophrenia, bipolar, depression etc would then under your examination be classified as mental health and curable by mental therapy, but has successfully been proven wrong, but also even almost everyone on the forum disagrees with you and I am certain that if you talked to Dr. Abraham, which I think you should do, he also will significantly disagree with you. Basically everything in the whole REAL universe of possibilities is telling you that you are in fact wrong. Yet you persist, which tells me you are possibly insane and/or narcissistic. To be completely honest you do not appear to have fully functioning mental faculties at this present time, you may have certain physiological derangements in the physical nature of your neuronal system that prevent you from attaining to such accurate and agreeable cognitive thoughts. As the famous 2 time nobel prize winning master and professional chemist Linus Pauling said, there is not ever seen mental health issues in a healthy brain. So, please shut the fuck up. What more evidence do you need? Do you need God to come from the heavens parting clouds with trumpets and lighting and riding beautiful unicorns to tell you that you are in fact wrong?
  31. 2 points
    Hey, for the best chance at recovery, the rules are pretty simple... Stay sober (inc. alcohol and caffeine), eat healthy, exercise, try to sleep well and just try to distract yourself as much as possible... Watch films, go for walks in nature.. Whatever works best for you. My personal opinion is you should try and get through a few months we zero input - no meds, no supplements. Just try to get used to your baseline with no added input. Good luck , Jay
  32. 2 points
    Since you got it from a "bad trip with visual hallucinogens", that is defining point of HPPD that is not VSS. But really, the diagnosing belongs to doctors who understand the disorder(s) --- good luck finding one. Also, to some degree the point is mute because there is no established medical protocol to treat either. You just have to try things with doctor(s) who are willing to help. Finally, people don't become schizophrenic or die from HPPD or VSS. It can just be very unpleasant and for some, interfere with work. The visual problems are 'illusions' not hallucinations. The anxiety (which most, but not all, have) can be reduced both medically and psychologically. As you already know, this picture produces the illusion of movement. If you are interested in understanding how this picture works, it relies on the brain's calculating dimension and distance. Most are familiar with the fact that having 2 eyes allows 'binocular' vision - understanding distance. A lesser know process is that the brain relies on contrast and shading to do the same function. In the case of this picture, the artist simply does shading deliberately inconsistent. So as the brain tries to figure things out, because it is inconsistent, the results are inconsistent, switching to one perspective then another. This creates the illusion of movement. As for HPPD, movement of 'static' objects is cause by the brain being uncertain as to what it is seeing so perspective again switches around creating the illusion of movement. Likely you will find the magnitude of effect depends both on what you are looking at and also the overall brightness. With HPPD, slight uncertainties can also affect attention/focus. Uncertainty drives one to vigilance which can increase anxiety. Explaining this (and hopefully people understanding this) can help one understand what is going on and thus help reduce anxiety about it - though it can still be annoying.
  33. 2 points
    Trying To Help is full of shit. I wouldn’t listen to a god damn thing he has to say about anything.
  34. 2 points
    Can you please stop bringing up the idea that anxiety is behind this... You have your own threads for that topic, don't bring them to other threads.
  35. 2 points
    When people post as he did, it is best to not get too caught up in it because the manor was unreasonable. Why? Troll? Egomania? Just over exuberant? Who knows. But his 'style' is not unlike people popping onto forums and posting, "If you just pray to Jesus sincerely enough, he will miraculously cure you". The reception to this is negative for obvious reasons. [ And if one is into the Bible, it grossly misrepresents the whole situation we live in now ]. The whole topic of controlling anxiety has been discussed and will be discussed and will remain an important tool. But anxiety <> HPPD.
  36. 2 points
    This is the same kind of bullshit that I've dealt with when trying to get help for this from "doctors". It's anxiety its all in your head. Stop thinking about it it will go away. Everyone that has to deal with HPPD/Brainfog/Depersonalization knows the frustration. I've tried to accept that this is all anxiety, but it's still here. It's a neurological disorder, plain and simple and I bet an FMRI can measure this. Has anyone ever heard of Pseudobulbar affect? Pseudobulbar affect (PBA) is a condition that's characterized by episodes of sudden uncontrollable and inappropriate laughing or crying. Pseudobulbar affect typically occurs in people with certain neurological conditions or injuries, which might affect the way the brain controls emotion. So is MattyHouseMouse suggesting that people with this Pseudobulbar affect can actually control there symptoms with shear will power? It doesn't work like that. If it could then what does that tell you about consciousness itself? Does the mind exist beyond our reality? And if it does then I guess with enough will power we could override any problem confined to our material world. I could literally grow a fucking leg back, or a brain.
  37. 2 points
    Matty O when he gets negative reviews... Were clearly not the only ones with a real condition here, if you think every person on this forum is makiing up their symptoms you’re probably clinically insane, and i agree, you should definitely go talk to real doctors, they will laugh at your immediate dismissiveness of mental disorders, just like they do the doctors of old who dismissed forms of insanity like schizophrenia. You sound ridiculous, you also appear to have a severe ego complex in my opinion. also its ridiculous to sign your name in forums especially since your screen name already shows Matty, we know who you are please do not be redundant. I’m guessing you’re young, if you want to do anything in medicine i highly suggest you do way more reading than just immediately jumping in to theory. ALSO, you claim facts but you provide zero evidence to support your claims, which also ,akes you appear to be ridiculous. All your posts in this thread are terribly cringy. You just have a belief with no evidence, but you feel strongly about it regardless, it makes you no better than a religious fanatic. P.S. The cure for male pattern baldness is swimming with sharks... once you see the shark it takes your mind off the hair loss and bam! All the hair is back, rogaine is now obsolete.
  38. 2 points
    I think you just want to justify your psychedelic consume because you already have mild HPPD but you still want to trip. However, if you continue to trip it will probably result in severe HPPD.
  39. 2 points
    One very severe counter-argument against your "theory": In 11 of 12 cases, taking phenothiazines worsens HPPD severely. For "normal" anxiety patients, they just work as a sedative. Many of the usual anxiety patients are also extremely worried about their health, so why don't they get HPPD when taking phenothiazines? It just does not make sense, there would have to be much more non-hallucinogen-induced cases. Even if not "trained" well, at least a small number of anxiety patients should notice the increase of visual phenomena caused by phenothiazines, get worried about it and falling into the "HPPD loop". But there are, as far as I know, 0 cases of people developing HPPD after phenothiazine usage without a past hallucinogen exposure. During my psychedelic expieriences, I completely didn't notice any of my HPPD symptoms. They suddenly occured more than a month after my LSD exposure, so I definitely did not have any "training". Some people suddenly get HPPD from one day to the next, years after hallucinogen exposure. How do you explain that? Why do many people exist who have very(!) strong visuals, but no anxious or emotional component at all? Why do some people have a sudden remission of visual symptoms from one day to another after years of "training"? My visual symptoms are not correlated in any way with anxiety. Sometimes I feel anxiety and visual phenomena are weak, and sometimes visual phenomena is strong and I don't feel any anxiety. For 3 months, I didn't feel any anxiety at all and barely put any attention on visuals, but visual phenomena was still getting worse with the same speed as befor and afterwards. Why do I have extreme mood swings from anxious to deppressive and (rarely) even euphoric expieriences which are very trippy. Do usual anxiety patients feel strong euphory just as under drug exposure? It was also normal and acceptable for me to take hallucinogens and I felt completely no anxiety about the use of the drug. During my bad trip and afterwards, within the first 3 months of my condition, there was not a single moment where I was not 100% sure that I'm safe and will be cured very, very soon. So why did I get HPPD? So many questions that cannot be answered by your claim. But I'd bring a counter theory into the discussion: People whose HPPD symptoms fade fast, persuade themselves that it was just imagination. No it was not. It was real for you, but you can't believe it as soon as you can't feel or see it anymore. You don't want to believe it. Your mind is rewriting the story in a way that you feel that everything is / was under your control. Because it doesn't want to accept that control is an illusion. And of course your mind favorites the explanation allowing you to continue hallucinogen use and having the control whether to develop HPPD or not. It's hard to admit that you don't have any control whether to develop this disorder or not. Everyone here knows that HPPD highly interacts with anxiety. There are people understanding this connection from the first day of their condition trying to work against their anxiety. "Stop being anxious" is a very good advice, but not a cure. Nobody knows if there is a brain damage or not. If someone suffers 40 years from this condition, and yes, there are such cases, I don't know what's the difference to a brain damage. You may say "the difference is that you can escape the loop", but remission can happen in cases of brain damage as well because the brain has the capability of working around the damage. Anyhow, you can assume that many patients do everything they can to get rid of anxiety. In the end it does not matter which theory is right. You cannot cure HPPD by saying it's anxiety-based just as you cannot cure depression by saying it's sadness-based. This discussion is damned to end in the middle of nowhere. There is no key and there will always be patients who are completely therapy-resistent, even if they are working harder on their cure than 99% of the other patients. Anyone can be cured, but not everyone.
  40. 2 points
    You're not a scientist, you don't know what the members of this forum experience visually and cognitively, you do not add anything constructive to the forum, therefore I think you posting here is totally useless and undesirable. If it was only anxiety, we would all be healed since most of of the people who seek medical help get misdiagnosed as having anxiety.
  41. 2 points
    David, What you're proposing looks very similar to https://www.reddit.com/r/HPPD/ which i imagine is one of the big causes of the decline in activity on this site. The simple true is that Reddit and Facebook have all but replaced forums like this and for good reason. However, that doesn't mean this site is a lost cause. There is a wealth of data, tips, positive stores, and other advice that can be organized and presented in a more useful way. Instead of competing with Reddit and Facebook, make this site into a hub of fact based information on HPPD. Organize all the success stores and positive coping treatments into sections that are easy to read. Have a FAQ about HPPD that addresses the fears we see posted time and time again. Harvest the data from this site into useful and easy to read statistic and info-graphs. Work with the Reddit and Facebook communities and become a resource to them. Have a way for people to easily donate money or time into research. Volunteers could pour through the old forum posts to tag and organize the data. Get some developers to create tools so that people can easily simulate their visual problems and compare them to others. Parter with the Visual Snow initiative as a lot of our symptoms overlap with that condition. This website should become the authority on HPPD, not just another reddit clone.
  42. 2 points
    Hi guys, 3 years ago, after excessive LSD and weed usage, I developed HPPD. At the time it felt like my life was over. my anxiety spiked, and I felt like my life would never be the same. I frequented this forum looking for cures and ways to deal with it, and this website helped me immensely along the way. I thought a good way to give back to this community would be to give offer some insight and advice to people going through this scary experience. 3 years after developing hppd, I would be lying if I said it had gone away. I still suffer from my symptoms, however, after a length of time, they become much easier to deal with. much like adapting to any other changes, life goes on and you get used to it. At the beginning of my HPPD journey, it was all I could think about. I resented myself for my stupid choices and thought that HPPD would be a constant daily struggle. these days, I barely even think about it. sure I notice the distorted vision and weird effects, but they have simply become a part of life for me now. the key things that helped me along the way: !Stop taking recreational drugs immediately! when I first developed HPPD, I kept looking for ways to use recreational drugs again. 'surely one-time won't hurt'. as unfair as it may seem, drugs are no longer compatible with you and you have to stop immediately. Accept that your HPPD may never go away. the quicker you do this, the faster you can get back to living your life and working on yourself. your symptoms may never go away, but your tolerance of those symptoms can drastically improve. Seek help if you need it. talk to friends, talk to a therapist. they may not understand the specifics about what you are going through, but they can help you work through the struggles. Most doctors will not know what HPPD is. pretty self-explanatory. you can try explaining it to them or not. I usually don't bother. Focus on self-improvement. This one is really important. HPPD can really fuck you up mentally. I became a nervous wreck and s still to this day suffer from anxiety. you need to figure out a personal process to work through these issues. whatever works for you. I want everyone struggling with HPPD to realise that life does get better again. It takes work and commitment, but I hope you can all get the point in your life where your HPPD does not hold you back from living the life YOU want. please do not hesitate to shoot me a message with any questions, or even if you just want to chat
  43. 2 points
    All these "success stories" are just acceptance. . . just stop. Has ANYONE ACTUALLY RECOVERED NOT ACCEPTED THEIR SYMPTOMS??!!?!?!? I can't live under a static sky for the rest of my fucking life. Honestly we should have another thread for ACCEPTANCE STORIES. RECOVERY IS DIFFERENT. ISN'T NEUROPLACICITY A THING?????
  44. 2 points
    Hello everyone This is the first time I write on the forum, but I have been visiting you guys for about a year now. I have had Hppd for that same amount of time. I am not going to write anything about myself nor my symptoms, except it might be important to mention that i have meditated for more than half my life, in a very serious manner. I would like to share something, since i am deeply engaged in eradicating Hppd from my system or at least from the neuralpathways that my consciousness observes. Psychedelics have in many experiments shown to increase neuroplasticity. Always portrayed very positively and for good reason, we don't generally have much plasticity. But negative plasticity can also happen..This is a qoute from an article "Successive dosing and increasing levels of tolerance implies stress-based neuroplasticity. In the case of hallucinogen persisting perception disorder (HPPD), the subject retains some of the visual effects of hallucinogens long after the drug should have metabolized;5 persisting reactions to neural stress imply neuroplasticity. " This resonates so much with me. About 4 months into Hppd i started to meditate daily for 1 hour, later making it 2. In the beginning it was tougher than ever before...It was like my mind was stuck in a loop and couldn'tfind its way back to meditation. I have been doing intense retreats since the age of 11, so it should have been fairly easy. But this was more painful than ever. Anyhow i pressed on, no matter how much it hurt, because it hurt a lot when i meditated. My head hurt so much that 1 time i nearly passed out. When practicing zazen we sit with open eyes, and the visuals would become extremely intense to the point of full on tripping again. So I pressed on day after day, and month after month. I could feel how my mind was slowly but surely breaking free from the evil spiral of Hppd. After some months the visuals when meditating died down, and the pain in the head became more bearable. I believe it will take quite a while consciousness to never dig into the dark channels of hppd again, maybe about 5 years. But that is fine. I believe that Hppd can be reversed with neuroplasticity. I will practice things that improve my neuroplasticity consistently and forcefully. Drawing, writing, dancing, learning a new language, training/yoga, daily meditation/zazen, proper sleep, playing a new instrument and so on. Good luck to all of you!
  45. 2 points
    Reddit /hppd is a cesspit of people who's main focus is to continue drugs after hppd use. You'll get positive feedback about taking fucking LSD with hppd over there.
  46. 2 points
    Thank you dasitmane for coming back on this forum, I was following your first thread with great pleasure. I hope that we can make some progress in our knowledge and that people will join in and share their findings. @yosoydiego About the Reddit thread, the connection with HPPD and Lyme was reported by a user who is actively promoting the use of chlorine dioxide to (falsely) cure HPPD. It is very unhealthy to practice this 'cure' and will not aid your mind and body in any positive way, so take that in mind when reading posts made by that user (HPPDandstuff).
  47. 2 points
    Understand, I'm not knocking the use of medications. Some people in this forum have had success with them. Why don't I take any? My symptoms aren't that bad at this stage in my life. I still have visuals, but I can live with that. I've had this disorder for over four decades and I've learned to adapt. Medications can have side effects and I'd prefer not to deal with that. In general, I'd prefer not to introduce any medications into my body unless I need them to live (if I got cancer for example). I've avoided blood pressure and lipid lowering meds through natural practices and life style changes. At this stage of my life, I'm happy and active. I'm not going to take anything that could possibly derail that. This is my path. I'm not suggesting that it's a better approach than anyone else's.
  48. 2 points
    Jay, thank you so much for your interest and being willing to film yourself! That is a great start for the documentary and I really appreciate you responding. In terms of other types of interview, I'm also seeking out those who may be comfortable showing their face. The documentary really all depends on how many people are willing to share their story and the way in which they want to share it. One of the things that I'm best at is something called rotoscoping, which is tracing over each frame of a video so that it produces a realistic animation (this was the method in the music video Take on Me). If I were taking the rotoscoping approach, I could trace everything except for the details of the face. So far, I've only had one person message me who is interested, but I really hope that people can see how much this documentary could help the public better understand and empathize with what we go through day to day. I'm guessing people may not be responding because of the anonymity issue, but even if people are willing to share their writing and read over it, I could change the pitch of their voice and make an animation that can visually represent what they are saying. Is there anyway to pin this post so more people see it? I really think this documentary could end up making a difference in terms of awareness and empathy towards people with HPPD. If certain people really respond to it, more research could be done.
  49. 2 points
    Hey Allen, First off, Congrats on the little one on the way buddy! As a father of two little ones I just wanted to assure you that In no way will HPPD determine the type of parent you are. I enjoy every second with my girls and they adore me. Now it may take me a little longer to read them bedtime stories with the text vibrating and all but they just think daddy is a slow reader lol. Best of luck with the meds, I unfortunately have never had any luck with them. I have a great career in the medical field and a wonderful family. HPPD sucks but I learned a while ago it doesn’t have to dictate your life.
  50. 2 points
    RE: Depression and Ketamine Infusion Therapy - WARNING! I wanted to share IMPORTANT information about a trendy treatment for severe depression/suicidality. That is, the use of ketamine IV therapy. It's expensive and there are news reports that it is a miracle for serious depression ( there's alot of stuff on youtube.com). My son had two rounds of Ketamine Infusion Therapy, and it seemed to work - we were (initially) quite impressed with the effects. Then I found a case report written by Dr. Abraham last year that shows the ketamine IV therapy CAUSED HPPD in an individual! If it causes HPPD, then it might exacerbate the HPPD, too. Please see the article... I am providing the online link, below, and attaching a PDF copy here. Salzman, Carl & David Abraham, Henry. (2017). Hallucinogen Persisting Perception Disorder Following Therapeutic Ketamine: A Case Report. Journal of Alcoholism & Drug Dependence. 05. 10.4172/2329-6488.1000281. Link: https://www.omicsonline.org/open-access/hallucinogen-persisting-perception-disorder-following-therapeutic-ketamine-a-case-report-2329-6488-1000281-93968.html PDF copy attached. Hope this information helps! Doreen Lewis, PhD hallucinogen-persisting-perception-disorder-following-therapeuticketamine-a-case-report-2329-6488-1000281 (3).pdf
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