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Hallucinogen Persisting Perception Disorder (HPPD) Support Forum


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  1. 2 points
    Hello everyone This is the first time I write on the forum, but I have been visiting you guys for about a year now. I have had Hppd for that same amount of time. I am not going to write anything about myself nor my symptoms, except it might be important to mention that i have meditated for more than half my life, in a very serious manner. I would like to share something, since i am deeply engaged in eradicating Hppd from my system or at least from the neuralpathways that my consciousness observes. Psychedelics have in many experiments shown to increase neuroplasticity. Always portrayed very positively and for good reason, we don't generally have much plasticity. But negative plasticity can also happen..This is a qoute from an article "Successive dosing and increasing levels of tolerance implies stress-based neuroplasticity. In the case of hallucinogen persisting perception disorder (HPPD), the subject retains some of the visual effects of hallucinogens long after the drug should have metabolized;5 persisting reactions to neural stress imply neuroplasticity. " This resonates so much with me. About 4 months into Hppd i started to meditate daily for 1 hour, later making it 2. In the beginning it was tougher than ever before...It was like my mind was stuck in a loop and couldn'tfind its way back to meditation. I have been doing intense retreats since the age of 11, so it should have been fairly easy. But this was more painful than ever. Anyhow i pressed on, no matter how much it hurt, because it hurt a lot when i meditated. My head hurt so much that 1 time i nearly passed out. When practicing zazen we sit with open eyes, and the visuals would become extremely intense to the point of full on tripping again. So I pressed on day after day, and month after month. I could feel how my mind was slowly but surely breaking free from the evil spiral of Hppd. After some months the visuals when meditating died down, and the pain in the head became more bearable. I believe it will take quite a while consciousness to never dig into the dark channels of hppd again, maybe about 5 years. But that is fine. I believe that Hppd can be reversed with neuroplasticity. I will practice things that improve my neuroplasticity consistently and forcefully. Drawing, writing, dancing, learning a new language, training/yoga, daily meditation/zazen, proper sleep, playing a new instrument and so on. Good luck to all of you!
  2. 2 points
    it's very funny because i remember long time ago i saw on a french channel a tv documentary about shamens , and he was called to cure a girl that was "stuck in the spirit world", ...seemed like hppd to me how they described it. The shamen came and used Sage to cure her, but i remember he burned it and she has to breath the fumes. What a coïncidence.
  3. 2 points
    Understand, I'm not knocking the use of medications. Some people in this forum have had success with them. Why don't I take any? My symptoms aren't that bad at this stage in my life. I still have visuals, but I can live with that. I've had this disorder for over four decades and I've learned to adapt. Medications can have side effects and I'd prefer not to deal with that. In general, I'd prefer not to introduce any medications into my body unless I need them to live (if I got cancer for example). I've avoided blood pressure and lipid lowering meds through natural practices and life style changes. At this stage of my life, I'm happy and active. I'm not going to take anything that could possibly derail that. This is my path. I'm not suggesting that it's a better approach than anyone else's.
  4. 1 point
    Hello everyone! Hope everyone is doing well. Been wanting to make a post for months now but just haven't been able to find time. The main reasons for my post is to share my progress and share what my methods were for the progress in hopes that others can possibly benefit from the same treatments. With very little notoriety and/or profit for medical science HPPD gets very little to no coverage at all, so I hope this is something to help those who are destitute in this insufferable and most terrible disorder and condition which could be described by none other than the manifestation of hell itself. To start I just want to explain that at the beginning of my condition I could scarcely drink 1/4 - 1/2 a cup of 12 oz coffee, I would often just discard the rest, anything more would initiate massive anxiety and increases in other symptoms involved with HPPD. Now, however, things have changed! I didn't really have much progress after about a year, things stayed relatively the same. I would, however, like to share a photo of how much caffeine I can consume, and explain how much I do consume daily, as a proof of improvement, that I do attribute to a various degree of long term treatment that is available to everyone. [ Here you can see the maximum amount of caffeine that I can now consume daily if I choose, it will give me minor amounts of anxiety, but its not beyond what I can handle, where before I could come nothing close to this. Don't be confused either, the coke I can drink whole as well, and the coffee thermos is 24 oz.. This is no where near what I was capable of consuming before, and took about 2-3 years to accomplish. On average daily since this is a bit much for me, I only drink the 24oz coffee, which I make every morning, coupled with a few supplements that have a mild stimulant effect. I've even been able to take minor amounts of stimulants that I always enjoyed before my condition(all legal of course). Its been a long road. So, here I will share two herbs that may potentially help you, I don't claim that it will resolve all your symptoms all together, I do still have issues, but they are significantly decreased from what they were. I do believe that this is a neurological disorder, but I atop the two herbs to share in potentially assisting the progression of the suffering from this disease, I do also have a possible alternative to the diagnosis to this disorder after researching very significantly microbiology for other reasons not involved with HPPD. Tomorrow in my next post I will explain the two herbs, I want to elaborate more so on the other possible diagnosis involving microbiology which is a possibility and will tie in to the treatment for both possibilities involved which I think everyone will be somewhat intrigued about. I hope everyone the best and hope you're all hanging in there and doing your research trying to improve this condition. Tomorrow I will post more and for sure elaborate on this condition and the possible treatments. I would like to shout out to Jay, Hope, Kozin, dayum_son, and a few others too but its been a while and I'll have to look up the screen names. Sorry for anyone that has PM'd me and I haven't responded I haven't been on for a while but I will try to be on more. I also wanted to post old information which is basically a sum up of my old post that I typed up for someone in an email which will save me a lot of time than typing it again. In my next post I will make an alternative possible diagnosis that is far different from the foregoing. I want everyone to know too that you're the greatest even if everyone abandons and leaves you in your suffering. Keep fighting to save yourself and bare your infirmities with this terrible disease and I hope anyone that leaves or abandons you adjourns their due justice in the universal law of karma to the fullest extent and then some if God so feels it. I hope too that you're all relieved of this curse that destroys lives and that people will supplicate to the suffering of the nightmare that we live waking. I hope to help you all in the next post. My heart goes out to everyone with this condition. Stay strong. The actual etiology, though often argued, is most likely to be a form of excitotoxic apoptosis following glutamate receptor overstimulation. It could also include variable causes including neuronal hyperthermia due to the overstimulation. This is commonly neglected as a possibility in health, research, and media, due to the fact that in MRI studies of HPPD sufferers and hallucinogenic users there is no "notable" damage that can be perceived. However I was able to accumulate quite a lot of MRIs from actual HPPD sufferers and there is a decent yield for white matter hyperintensities, enough to be suspect for possible neuronal degeneration. The white matter lesions also appear to be long standing ruling out temporary axonal demyelination. Another point to be shown that it neuronal loss should not be ruled out is the obvious fact that MRIs are only subject to detecting larger unscattered masses of neuronal lost such as that found in blunt trauma victims and stroke victims etc, but unbeknownst to your average physician its incapable of showing minute scattered neuronal loss which can be seen in the link of this lithium overdose patent. Case Report A 45-year-old Mr. S presented with a history of altered sensorium for the past 2 days. The patient had a history of five episodes of mania and two episodes of depression in the last 15 years. Six weeks ago he had an episode of mania, for which he was treated at a tertiary care center as inpatient and given a tablet each of olanzapine 20 mg, lithium 900 mg, and chlorpromazine 300 mg daily. A week after he was discharged from the center, while still on regular medication, he developed coarse tremors affecting the whole body and was unable to walk. When he was brought to the Accident and Emergency Department of our hospital, he was afebrile and was not responding to painful commands. His pulse rate was 105/min with exaggerated deep tendon reflexes. His investigations showed a raised serum lithium level of 3.9 mEq/L, creatinine of 1.8 mg/dl, and raised white blood cells of 24,800/μl. His liver function tests and sugar level were within the normal range. All his previous medications, including lithium were stopped, and he was treated with intravenous (IV) normal saline, IV ceftriaxone 2 g, and vancomycin 500 mg twice a day for 2 weeks. In order to rule out any infection, his blood was sent for culture, and a cerebrospinal fluid (CSF) analysis was done to rule out any neuro-infection. However, both blood culture and CSF results were found to be normal. A magnetic resonance imaging (MRI) of the brain showed T2 and flair hyperintensities in the bilateral parietal lobe and periventricular white matter changes, both suggestive of lithium toxicity [Figure 1]a. In view of his low Glasgow coma scale (8/15), the patient was intubated. Also, because of the severe lithium toxicity, hemodialysis was started. After two cycles of hemodialysis, the patient started responding to painful commands. His serum lithium level fell to 1.8 mEq/L. He was extubated on day 5 of admission. From day 6 onward, he started responding to oral commands, even though his speech was slurred. However, he had coarse tremors, truncal ataxia, and difficulty in deglutition. Subsequently, the patient was shifted to the psychiatry ward of our hospital for further management and for observation of manic symptoms. Physiotherapy was started, and within 2 weeks of intensive physiotherapy the patient started walking with support. His speech too improved. After 3 weeks, when his blood serum lithium level fell to 0.2 mEq/L, he started showing symptoms of mania. He was then treated with oral quetiapine, which was gradually increased to 300 mg/day. Thirty-six days after the first MRI, a second MRI was done. The second MRI showed up to 40% reduction in periventricular white matter hyperintensities in the bilateral parietal lobes [Figure 1]b. Even after about 6 months of follow-up the patient continues to have coarse tremors, dysarthria, and significant limb ataxia. Brain MRI showing hyperintensities.  So even after 6 months he was showing symptoms, which clearly demonstrates damage to the neural tissue. A clear example that MRIs are not completely effective and accurate in diagnosing neuronal loss. There are countless examples that be given to prove this, another is even in epileptic patients who are taking anticonvulsant medications as treatment, proven neurotoxic compounds, MRIs will only show neuronal loss after 10-20 years and will only show it as encephalopathy. So media and medicine claiming that this hallucinogenic compound are "safe" are ignoring a LOT of information. Heres just one of many abstracts that show through the study of MDMA that activation of 5ht2a receptions(those activated in hallucinogens) are neurotoxic Abstract 3,4-Methylenedioxymethamphetamine (MDMA or "Ecstasy") and 2,5-dimethoxy-4-iodoamphetamine hydrochloride (DOI) are hallucinogenic amphetamines with addictive properties. The hippocampus is involved in learning and memory and seems particularly vulnerable to amphetamine's neurotoxicity. We evaluated the neurotoxicity of DOI and MDMA in primary neuronal cultures of hippocampus obtained from Wistar rat embryos (E-17 to E-19). Mature neurons after 10 days in culture were exposed for 24 or 48 h either to MDMA (100-800 μM) or DOI (10-100 μM). Both the lactate dehydrogenase (LDH) release and the tetrazolium-based (MTT) assays revealed a concentration- and time-dependent neuronal death and mitochondrial dysfunction after exposure to both drugs. Both drugs promoted a significant increase in caspase-8 and caspase-3 activities. At concentrations that produced similar levels of neuronal death, DOI promoted a higher increase in the activity of both caspases than MDMA. In the mitochondrial fraction of neurons exposed 24h to DOI or MDMA, we found a significant increase in the 67 kDa band of apoptosis inducing factor (AIF) by Western blot. Moreover, 24h exposure to DOI promoted an increase in cytochrome c in the cytoplasmatic fraction of neurons. Pre-treatment with an antibody raised against the 5-HT(2A)-receptor (an irreversible antagonist) greatly attenuated neuronal death promoted by 48 h exposure to DOI or MDMA. In conclusion, hallucinogenic amphetamines promoted programmed neuronal death involving both the mitochondria machinery and the extrinsic cell death key regulators. Death was dependent, at least in part, on the stimulation of the 5-HT(2A)-receptors. https://www.ncbi.nlm.nih.gov/pubmed/22983118 Risperodone is a good case too for showing excitotoxic damage, a 5ht2a inverse agonist, and other anti convulsion medications which are 5ht2a antagonists there is a correlation with palinopsia. Palinopsia being obviously common with HPPD, the most probable reason being, that the 5ht2a specific neurons that underwent glutamate excitotoxic apoptosis, are now gone, and therein laying a lack of 5ht2a input, which would be similar to that of these drugs, being inverse agonists and antagonists. So this gives even more credence that HPPD is caused by 5ht2a induced glutamate excitotoxic apoptosis. So unfortunately for these sufferers is most likely that their diagnosis is neuronal loss. A sad day for anyone regardless if they are a drug addict or a one times user. Heres a study that shows the areas likely to be affected Brain imaging studies Until recently, many neural circuit models were based on animal studies, and implications for the effects of hallucinogenic drugs or disease models in humans were based on inferences from these studies. However, functional neuroimaging studies enable one to examine these neural circuit models directly and test specific hypotheses about the role of specific neural systems in the expression of ASC. PET with the radiotracer 18F-fluorodcoxyglucose (18FDG) was used to assess drug-induced changes in the regional cerebral metabolic rate of glucose (CMRglu), as an index of cerebral activity. We found that a hallucinogenic dose of racemic ketamine increased neuronal activity in the prefrontal cortex (hyperfrontality) and associated limbic regions, as well as in striatal and thalamic structures in healthy volunteers, giving the first evidence that functional alterations in CSTC loops may underlie the symptomatology of drug-induced ASC.50 This hyperfrontality finding was corroborated and extended in subsequent studies in healthy volunteers in which the effects of hallucinogens and NMDA antagonists including psilocybin, racemic ketamine, and S-ketamine were compared. In particular, we found that, despite different primary mechanisms of action, the two classes of drugs produced strikingly similar brain activation patterns as indexed by normalized CMRglu. Both psilocybin and ketamine markedly increased brain activity bilaterally in the frontomedial and frontolateral cortex, including the anterior cingulate. Lesser increases were found in the temporomedial, superior, and inferior parietal cortices, striatum, and thalamus. Decreases were found in the left caudate nucleus, bilaterally in the ventral striatum, occipital lobe, and visual pathway.9-11 A correlational analysis revealed that the metabolic hyperfrontality in ketamine and psilocybin subjects was associated with a depersonalization/derealization syndrome, thought disturbances, and mania-like symptoms.9-11 The hyperfrontality finding in ASC was further supported by evidence from brain imaging studies with ketamine and psilocybin in healthy volunteers27,51 and was also found in subjects treated with the classic pheny le thyl amine hallucinogen mescaline.52 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181663/ Prognosis is typically really bad with little recovery in patients that have extensive damage. Mainly the only saving grace is synaptic hyper plasticity. If you then take in to account the possibility for future advancements in neurogenesis and stem cell research there is some hope but there is the unfortunate case that regeneration of damage to the white matter shown in Axolotl Salamanders is structural deficient when taken in to account long distance axonal tracts. The Axolotl being capable to regenerating neurons sadly only can fill the area of these damaged long tracts with short neurons typically found in gray matter, making structural integrity likely deficient in functional regrowth. So even with neurogenesis prognosis is likely grim for these patients. There is a certain drug that I found that ends the cascade event of hallucinations right at the core of the matter and would in the event of a "bad trip" save these patients a great deal of permanent neuronal loss if they made it to the ER in time. I cant find the drug at the moment and I don't have time to find it but I believe it was simply an reverse 5htp2a receptor agonist. I was actually able to find some treatments in extremely old medical books too, which lead me to believe that the physicians were actually stimulating neurogenesis in their patients, but still even with that recovery is limited due to axonal tracts being lost in white matter, but it would certainly improve their lives. Instead of educating people of these dangers they promote hallucinogens as potential for all kinds of treatments and ignore negative effects. One study showed in 400 people who were given hallucinogens 157 report long term effects that did not resolve, some committed suicide. Heres the axolotl research The axolotl can regenerate multiple organs, including the brain. It remains, however, unclear whether neuronal diversity, intricate tissue architecture, and axonal connectivity can be regenerated; yet, this is critical for recovery of function and a central aim of cell replacement strategies in the mammalian central nervous system. Here, we demonstrate that, upon mechanical injury to the adult pallium, axolotls can regenerate several of the populations of neurons present before injury. Notably, regenerated neurons acquire functional electrophysiological traits and respond appropriately to afferent inputs. Despite the ability to regenerate specific, molecularly-defined neuronal subtypes, we also uncovered previously unappreciated limitations by showing that newborn neurons organize within altered tissue architecture and fail to re-establish the long-distance axonal tracts and circuit physiology present before injury. The data provide a direct demonstration that diverse, electrophysiologically functional neurons can be regenerated in axolotls, but challenge prior assumptions of functional brain repair in regenerative species. https://doi.org/10.7554/eLife.13998.001 This how complex the tracts are Interneurons a possibility, Dr. Abraham comments on this LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex. Marek GJ1, Aghajanian GK. Author information Abstract Correlations between 5-hydroxytryptamine (5-HT) receptor binding affinities and human hallucinogenic potency have suggested that 5-HT2 receptors mediate the hallucinogenic effects of lysergic acid diethylamide (LSD) and phenethylamine hallucinogens. Electrophysiological studies have suggested that a subpopulation of gamma-aminobutyric acid (GABA)ergic interneurons in layer III of the rat piriform cortex are excited by serotonin (5-HT) via 5-HT2A receptors. These interneurons have inhibitory inputs on pyramidal cells in layer II. In the present study, we tested low concentrations of both LSD (3-100 nM) and the phenethylamine hallucinogen 1-(2,5-dimethoxy-4-iodophenyl-2-aminopropane (DOI; 0.3-10 microM) on rat piriform cortical interneurons that were excited by 5-HT. Both LSD (3-100 nM) and DOI (0.3-10 microM) excited almost every cell excited by 5-HT. The maximal excitation achieved with LSD and DOI was 39% and 55% of the effect of a near-maximal 5-HT concentration (100 microM). Consistent with a partial agonist action, LSD and DOI blocked the 5-HT excitation of piriform cortical interneurons only at the higher hallucinogen concentrations tested. A specific 5-HT2A receptor antagonist, MDL 100,907, blocked excitation of these interneurons by 5-HT, LSD and DOI, but not by norepinephrine or alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate. Again, consistent with a partial agonist action of the hallucinogens, intracellular experiments showed that a maximal concentration of DOI (10 microM) induced fewer postsynaptic inhibitory currents than did 5-HT (100 microM) in pyramidal neurons in layer II of the piriform cortex. Based on the present electrophysiological studies, we conclude that LSD and DOI, a phenethylamine hallucinogen, act as highly potent partial agonists at cortical 5-HT2A receptors.
  5. 1 point
    HUGE post today. Last night I was reading an LSD study and the effects on the brain, going on about areas that are upreg/downreg or something. Anyways the down regulated areas he mentioned are desyncronized. I had to look up what that meant because I had no idea, but it started going on about brain frequencies etc. Basically the neurons in areas pulse with a feed back loop from other areas through resonance, the neurons fire in waves, as groups, its exactly what I was talking about really early on in my first thread. So I started conjecturing that maybe in a few minor users of hallucinogens their brain becomes permanently desynced so to speak, or the harmony between the two areas become discordant, exactly like I used to conjecture, only now there is physical evidence to the idea being possible. So, it comes back to the very first and original posts I made here when I joined 7-8 years ago, about using an antagonist, or maybe even an inverse agonist to "resync" the brain areas. It appears that the issues are predominately in the temporal lobes for people who have anxiety, and the occipital lobes for visual effects. I found a study involving Dr. Abraham where they did EEG studies on post drug users with and without anxiety, most of the users with anxiety showed irregularities in these areas, these are also areas in with patients with seizures can be effected. Dr. Abraham and the other doctor also mentioned how before seizures, patients will report high fear/anxiety. The condition of HPPD could very well be brother/sister relationship with epilepsy interestingly enough. Then I searched the HPPD forum for any posts involving 5HTP2A receptor antagonists or agonists. What found is shocking. Heres the posts from "Victor" Posted March 31 In my case the disorder healed in two months with risperidone and paroxetine. Paroxetine acting upon anxiety and risperidone over visual distortions. Well you know the risk of self-medicating, do not do that, I had facial spasms with only 3 days of use of quetiapine (prescribed by shrink). Doctors actually know about the disorder, but since it is something very recent and vague hardly anyone is diagnosed with it, even because sequels of psychedelic drugs are not the only reason for the cause of false visual perceptions or other senses without loss of lucidity. So go to the psychiatrist anyway, because only then will you get these medications and then heal. Other than this, physical activities are great for diverting your focus from the problem, but the visual symptoms will only disappear with treatment using remedies. I also suggest meditation and some artistic activity such as writing, drawing, playing an instrument, etc. And also temporary abolition of coffee, alcohol and cigarette consumption. Posted March 25 Hello ! Your story is very similar to everyone here, including mine. When I had HPPD, I also got the symptoms very fast and only noticed them after smoking marijuana days after my trip with LSD. What matters is that as quickly as the symptoms came, they left. This is because I did psychiatric treatment, initially using paroxetine for anxiety, risperidone for visual distortions and clonazepam for anxious seizures. Risperidone is an antipsychotic and a major antagonist of LSD as well as quetiapine and chlorpromazine (I have taken all of these, but risperidone was the most effective). In a matter of two months the false hallucinogenic perceptions were gone. With you it would not be different, but for this you need to look for a psychiatrist and explain what happens to you, as he will know the right medication to apply. Please do not self-medicate, as these medicines can have horrible adverse reactions. I for example had facial spasms when I took quetiapine (this I only took for 3 days). I recommend that you do not look for it on the internet, because it is still very vague, unfortunately it is difficult to find information about it and almost all are scary, as it comes from a sensational and anti-drug media. Rest assured, what happens to you is nothing serious and has a cure. Avoid using drugs at this time, including marijuana, alcohol, cigarettes, and coffee. Stay in peace ! If you read most of his posts he is very adamant that Risperidone cured his HPPD. I found another poster too... Posted October 26, 2013 I have HPPD consisting of marihuana-like derealization, LSD-like movements of surfaces, and optical noise. The LSD-like movements had gotten much better over the course of 7 years until they were barely noticeable, until I took Ritalin. Within two weeks, the LSD effects were almost as bad as in the beginning. The rest of my visual effects were not affected. I discontinued Ritalin. The LSD effects remained unchanged (other than going through their usual cyclical fluctuation over 5 days (IIRC) for the next few weeks. Then I started taking low-dose Risperidone (2mg, I think). For the first two days, nothing happened. On day 3, the LSD effects were basically turned off, back to barely noticeable. It was like flipping a switch. In the morning they were there, in the afternoon they were almost gone. I continued taking Risperidone for a few weeks, even increased the dosage, but nothing else happened. There was no effect on my other visuals. After discontinuing Risperidone, the LSD effects did not return, even when I started taking Ritalin again (strange, huh?). I've been taking Ritalin for a few years now. The HPPD symptoms are stable. Caffeine never affected my symptoms. I also found another poster saying he was cured by 200mg of Lamotrigine, which is an antiseizure medication, but it would be clear that this would only treat the symptoms since they are probably similar to epilepsy like disruptions in the brains resonations. Also, there are arguements that Risperidone, an inverse agonist of 5HTP2A exasperates symptoms of HPPD, which is also probably very true, as per the drug in itself without history of HPPD can cause palinopsia. I'm guessing the difference is just in the dose, as the one guy listed his dose which was very smart of him, and as far as I'm concerned is a pretty low dose, not the lowest, but pretty low, as the high does is 200mg. So the answer may very well be in inverse agonists, and maybe even antagonists as well. whichever being the case I'm not entirely sure. Interestingly enough this is probably the "reversal" that hope's research team may have in mind, whether they read my initial ideas/post in my first thread I have no idea, and if that is what they have in mind I'm not entirely sure. But this may very well be it. The cure for HPPD.
  6. 1 point
    I am feeling really really good when I am on keppra. I take 250mg when I wake up and it knocks out my DP completely. It also kills the brain fog. I noticed a 30% reduction in CEVs so far. When Keppra starts to wear off I notice an increase in DP. I Guess I have to take the second pill earlier. I am on 500mg and I will add 250mg every 2 weeks until I reach 2000mg or when I will start noticing side effects. So far I dont notice any side effects anymore unless feeling awesome is a side effect. I have hppd for only 3 months. I think with enough time, healthy lifestyle(keto) and the keppra treatment it can go away completely.
  7. 1 point
    This is all really interesting because I distinctly remember my visual snow not appearing until about 2 weeks after getting HPPD, I didn't have the slightest clue what was going on at the time. In retrospect I just figured it had something to do with macro clean up in the nervous system of the damaged tissue, but it could have been increased growth of infection in the central nervous system. There is a member on here as well that spoke well of how he did hallucinogens and was fine but then a couple months later got really drunk and bam HPPD, which could be infection breach due to alcohols ability to disrupt the epithelial barrier. Really interesting stuff. WHen you go back for antibiotic treatment take note of your symptoms. Granted, some bacteria are not susceptible to all antibiotics, so this is a dilemma, and some are multi drug resistant strains, so its possible to see no effect at all. If anyone has had extensive antibiotic therapy and noticed a difference in symptoms during their treatment please post. Thank you!
  8. 1 point
    This has been mentioned before but it seems like as soon as it is mentioned there is a backlash from several people in the HPPD community, like it is totally absurd to even bring up a possible connection. If we really want to find a "cure" for HPPD, we really need to dig into everything, even if it is unprobable, to make sure we haven't missed something.
  9. 1 point
  10. 1 point
    That's exactly what i do since 20 years. My brain is similar as a child one, I have an unquenchable thirst for new things to learn. I guess that's what made me "successful" in my lifestyle. Never tried real meditation , but i will try to .
  11. 1 point
    Awesome, congratulations! Keep updating!
  12. 1 point
    Yeah it’s stupid...
  13. 1 point
    I remember when I was reading studies done about hallucinogens changing the way we learn etc..... Anyone involved in those studies I would remove from practicing medicine or doing research if I could. Personally I'd say this sounds pretty dumb.
  14. 1 point
    Exciting news! I've reached out to Dr. Henry Abraham (for those of you who don't know him, he was the lead researcher of HPPD who also coined the term and put it in the DSM) and he would like to be a part of this documentary. I'm planning on interviewing him during the winter and will be taking a trip down to Florida. If anyone in the US is on the way (East coast between Virginia and Florida) I would love to stop by and capture video and interview if anyone is willing! (Reminder that all identities can be hidden to protect you). I am so excited that Dr. Abraham will be a part of this and can take this documentary to the next level. Again, if anyone is interested in being a part of this whether it is interview, sharing your artwork, sharing writing, voice recordings-- ANYTHING do not hesitate to reach out!
  15. 1 point
    Reddit /hppd is a cesspit of people who's main focus is to continue drugs after hppd use. You'll get positive feedback about taking fucking LSD with hppd over there.
  16. 1 point
    Indeed, sorry that I was offline for a few days and couldn't update on that, but I realized that immediately. Also edited my post there to make it less relevant, and also thought about posting warning of the dangers of chlorine dioxide, MMS, and all that sh*t, but I realized it was done already... and the desperate people will ignore all those warnings anyway, so there isn't much that we can do. That sh*t is even being fed to autistic kids... I hope the "brains" behind it all rot in hell. So, I'm sorry for linking to that topic. Having said that, despite the bullsh*t of the MMS and the likes, I'd not disregard the bacteria idea, or something similar, just thinking out of the box, as dasitmane is doing too. I keep thinking that the current hppd "understanding" makes no more sense than any random weird hypothesis.
  17. 1 point
    Yes I'm not very smart. Let's say that I did many drugs before I knew what HPPD was. From worst to least effects : -Acid (no shit Sherlock) -Weed -Ketamine -MDMA -4-MMC (Mephedrone) -Alcohol -Nicotine -Cocaine Even though I am talking about "worse" effects, HPPD returned to baseline in a matter of a week (3 weeks for weed though). But I never was a huge consumer and always consumed within safe dosages, without mixing and with reasonable intervals between each sesh. And tested all my drugs, so I guess that helped. Drugs are bad m'kay ? 😂
  18. 1 point
    Thank you dasitmane for coming back on this forum, I was following your first thread with great pleasure. I hope that we can make some progress in our knowledge and that people will join in and share their findings. @yosoydiego About the Reddit thread, the connection with HPPD and Lyme was reported by a user who is actively promoting the use of chlorine dioxide to (falsely) cure HPPD. It is very unhealthy to practice this 'cure' and will not aid your mind and body in any positive way, so take that in mind when reading posts made by that user (HPPDandstuff).
  19. 1 point
    Currently experimenting , just to thick that box. Sage food supplement 3x450mg / 2 times a day Will leave comments
  20. 1 point
    Salvia (Sage): A Review of its Potential Cognitive-Enhancing and Protective Effects https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318325/ Hallucinations - acetylcholine https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996210/ Acetylcholine and hallucinations: disease-related compared to drug-induced alterations in human consciousness. https://www.ncbi.nlm.nih.gov/pubmed/8546852
  21. 1 point
    Sleeps problems is what I'm having at the moment, and only that, and it has me worried. I wouldn't call it "only sleep problems", because sleep is extremely important for our wellbeing!!! I recommend reading the book Why we sleep, or listening to talks of the author.
  22. 1 point
    I've never taken medications for this disorder. Well, not exactly true. In my 30s I drank a bit more than was healthy. Back when I started noticing symptoms it was the 1970s. There weren't a lot of options back then. Now, I manage just being clean. If you dosed just that one time, and you're staying clean, then your prospects are good.
  23. 1 point
    Hey All! It's almost been two years now with HPPD, coming up on June 2nd. Man, it's been a hell of a fucking ride. I don't know where to start, I've grown so much since getting it when I was 16, I'm 18 now. I'm graduating from high school in 15 days. This site has been in my life less-so in the past year, but you guys really gave me the guidance I so needed as a confused 16-year-old. I just wanted to come on and say thank you for all the guidance and love. Just wanted to say my symptoms really have almost gone away, like 90% gone! It's just the fucking depersonalization and sadness I feel that stay with me regardless of the change I've gone through. Even though I feel this way, life is only going to get better from here! To another year! Andrew A.K.A Originally Lizard_1.mp4
  24. 1 point
    Hey guys, I have HPPD since a just little more than 2 years now (happy birthday to it), and the symptom that get in the way of living a normal life the most is pressure in head and around the eyes(my vision is foggy according to how much pressure I feel, the rare moments when I have no pressure my vision is clear) Ofc I did all the classic exams which all came back fine lol. I would like to know how many of you have this too ? And have you found some ways to relieve this ? So far only caffeine proved to be helpful to an extent I don't mean this to disrespect people who have "only" visual symptoms but I could live with them if I didn't had this constant pressure in my face
  25. 1 point
    About a half a year ago, after a trip, I started having symptoms of HPPD. I had visual snow, and huge starbursts at night. I saw lots of BFEP, I had an intense amount of floaters in my vision, and I could hardly look at any light, or tv screen, or (god forbid) projected PowerPoint presentation without getting horrible afterimages. I had bad denationalization, and I constantly had the feeling that I was living in a dream world, and was having constant panic attacks. After two months most of the denationalization had faded away, but I still had the afterimages, and floaters, and other visual symptoms. After another month, I noticed that I could look at lights, and the afterimages would fade much more quickly. I also noticed that the floaters were only visible in bright light, they were previously visible in even a dimly lit room. Another month later and I could hardly see the floaters anymore. I barely got afterimages, and could drive in the dark without getting bothered. I could look at screens, and don't see swimming dots. I hardly see floaters anymore, unless I look at a white wall or blank sky. I didn't do much specifically to aid in my recovery. I tried out some supplements recommended on this board (lions mane, ginkgo, b vitamins, fish oil). I didn't notice any difference until months after I started taking them, and have since stopped, and not noticed any symptoms returning. I don't think they helped me with my recovery, but I can't be sure, because I was taking them at that time. During the entire time since I got HPPD I have not done any illicit substances at all. I have drunk alcohol however, and have had many weekend nights when I was drunk. This had a negative effect, at the beginning, but after I got over the denationalization, I didn't notice any increase in negative effects from drinking I think that it was mostly time that helped me get cured. It took about 4 months from the time my symptoms started till I could say I felt normal again. I count myself extremely lucky that things improved as quickly as they did I have been away from this website for a while. After the first three months I was able to handle my life without using this website. I would not have come back, except that I wanted to post about my good news. When I first started reading this site, I was scared, and reading positive results like this made me feel less terrified. For those of you who are like me a half year ago, it's been a few weeks and you're still seeing thing, just know that some people do recover.
  26. 1 point
    I'm 4 and a half months in and haven't quite recovered yet but its definitely better than after the first month. It truly is a demon like no other. But I feel confident that maybe within a year or year and a half I will be back to normal. Hearing yalls stories gives me tons of hope!
  27. 1 point
    I've talked to my friends about it and found out three of my friends have gone through it. one has lasted for the past couple years and continues but it barely bothers him now. The other two of my friends are completely cured. Took one of my friends 6 or so months to get better and my other friend got better after two years. Both of these people still use drugs regularly and its never came back. I thought i'd share this to give some people a little hope, i know it did for me.
  28. 1 point
    I wish there was an example of 100% recovery. Not the usual, "im successful but I can still notice some symptoms." Although this is not an HPPD success story, I do have a brain success story. There was a time, after a heavy night of drinking, I developed mild vertigo. (Havent tried mdma/lsd at this point. only weed. anyways,) It took me about 6 month to recover from it. As one of the other post mentioned, our brain does count in months and years so try to not to worry about it on a daily basis.
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