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Old article about the brain and LSD


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Was just browsing Google for LSD-related articles when I stumbled upon this from about five years ago: https://blogs.scientificamerican.com/scicurious-brain/httpblogsscientificamericancomscicurious-brain20110802sciam-chemistry-day-lsd-a-drug-only-as-good-as-its-receptors/

Pretty interesting summary of the brain on LSD. I'm not sure if there's been more in depth studies since then but I feel this is a good starting point for those who don't understand what happens inside the brain on acid. 

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  • 5 weeks later...

"But right now, scientists think that the effects that the 5-HT2A receptor has on glutamate signaling are the ones responsible for the sense of dissociation, the sensory distortion, and possibly those weird wavy lines."

It's strange that APs that block 5ht2a don't work well for HPPD and dissociation.

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