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Clinical characteristics of individuals with schizophrenia and hallucinogen persisting perception disorder: a preliminary investigation

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Sounds like an unsure conclusion in that study.

They should test people with only hppd and see if some of the symptoms jibe.

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I wonder how they tested this.

I also wonder if they know the genes that give a predisposition to schizophrenia, aided by the use of hallucinogens into an actual schizo disorder.

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Don't mean to tack on another study but this is vaguely related.

fitchlab.com/FitchLabBin/AnimalModelsDownloads/Hida.etal.2013.pdf

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I dont know why but this scares the shit out of me. The good old afraid of getting crazy paranoia i guess

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http://www.ncbi.nlm.nih.gov/pubmed/25392249

 

The full version of this article is not free. I think it's interesting that many of the patients with schizophrenia and HPPD can differentiate between their psychotic symptoms and HPPD symptoms.

 

This is significant.  How to medically treat could be problematic.  

 

First, if any are 'dopamine-responsive', they can't be treated that way without making the dillusions worse.  (Don't worry Merkan, if you were schizophrenic, your Sinemet would have you over the edge).

 

Second, how many of these suffer schizophrenia from drug use?  Or have been made worse from the meds to treat psychosis?

 

Third, for those not showing any relationship between HPPD and dopamine, these would provide a study group that filters out the ~30-40% dopamine responders (tolcapone + sinamet)

 

Tolcapone-percent-reduced-Sx.png

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So you are saying that there are individuals with both schizophrenia and HPPD? Then I'm not going to whine no more.

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