andrewcb Posted August 28, 2014 Report Share Posted August 28, 2014 I've been using SAMe for almost 3 weeks now. Started off at 400 mg a day, than 800 mg a day and now I am just taking 1600 mg in the mornings. Sadly it isn't doing anything, it is like taking nothing. I am wondering if it is the brand I am taking so might try a different brand next time. I am going to attempt to take it sublingually today to see if that works. Well, just curious if anyone has tried this product, I am using it for depression/anxiety/motivation in conjunction with Selegiline. Link to comment Share on other sites More sharing options...
Mr.50's Posted September 1, 2014 Report Share Posted September 1, 2014 funny i was just looking up that stuff sad to hear it has no benefits. im pissed cause my gnc doesnt have it but maybe yours might, mucuna dopa. its contains l-dopa, sinemet is pure l-dopa mucuna dopa is 15% l-dopa. it also contains like 30 othe things needed to producedopamine sam-e is only 1 Link to comment Share on other sites More sharing options...
StateOfRegret Posted September 2, 2014 Report Share Posted September 2, 2014 Just to correct one thing; Sinemet is not pure L-dopa. It is L-dopa and carbidopa. Carbidopa is responsible for inhibiting the breakdown of L-dopa outside the brain, allowing it to enter the brain itself. Carbidopa is pretty essential to the effectiveness of Sinemet. Link to comment Share on other sites More sharing options...
Mr.50's Posted September 2, 2014 Report Share Posted September 2, 2014 yes your right stateofregret, but there's ways around that. im 16 and my mom has no idea ive ever touched drugs or that i scrambled my brain like an egg from them, so that means i cant get medication through my doc without tellin my mom why. so when i saw that l dopa in the mucuna dopa extract, is 100% sinemet with just with other herbs and stuff in this mucuna dopa extract, i researched it like crazy. how in the fuck could a hppd medication be sitting at my gnc without me needing a prescription to pick it up, i got so excited. but i read wha thappens when you take sinemet or mucuna dopa without carbidopa, scary shit all because you have dopamine that didnt go through the blood brain barrier floating around. i also read that green tea, is a natural comt inhibitor, it breaks down said dopamine to allow it to cross the blood brain barrier, theers like 20 articles about this. so amzingly, you dont need carbidopa when taking low dose l-dopa, just green tea. Link to comment Share on other sites More sharing options...
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