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Hi all, I tried to register with this forum around 4 years ago but every email address I used was never sent a confirmation email. So finally I am registered and hope that my experiences can help other and I can gain help from others experiences. In the year 2000 when I had not long turned 16 I noticed that something called salvia divinorum was being advertised on the internet as a legal trip. I had only used solvents and smoked cannabis at this stage and was scared of chemicals like mdma and amphetamines but was interested in natural highs like mushrooms, dmt and acid. I ordered a bag of the standard leaf and smoked a fairly small bong of the leaf and lay on my bed in the dark and started to notice neon cartoon patterns moving around and found the short experience very pleasurable so the next night I smoked a bong of hash first then two large bongs of salvia and lay on my bed with the light on. Almost staight away my bed looked like it was starting to spin off into infinity and my body was beginning to drift away on the rings, I was loving it at this point then I remembered that I was told it's normally better to take it in darkness so switched off my light and lay back on my bed, this was the biggest mistake I could ever have made as almost instantly the trip became overwhelming, serious and frightening, my bedroom furniture started morphing into letters that were marching around the room, then everything I knew as real started to disappear and I couldn't see my body and became surrounded in pixelated patterns that kept getting larger and larger while my heart beat got faster and faster, it reached a point of intensity that I had a sudden thought that if I don't get the light back on I'll be stuck here in this weird pixelated place with no body or my heart will keep getting faster until I die. As I couldn't see anything real I was panicking frantically feeling around for the light switch and finally got it on and thankfully things calmed down pretty quick after that but I was still in a state of distress and panic, I ran through to the kitchen and grabbed a handful of sweets from the cupboard and his under my duvet cover and tried to calm down, this was when I noticed for the first time I was having closed eye visuals and the flavours of the sweets were changing the colours and shapes of the visuals. I was told that this stuff was supposed to last around 30 minutes and this was now more than 3 hours into the experience. The closed eye visuals have never stopped since then so now when I'm tired and want to relax if I lie down and close my eyes my eyes are always still open on the inside and depending on how I'm feeling or if I've had any sedative type of medication will depend on if it is possible for me to close my eyes and relax or if closing them throws me into a rollercoaster ride of fractal style patterns that I can feel my body move with as the patterns change, spin and move in waves. The exact same thing happens when it starts to get dark and if I'm in total darkness it makes no difference if my eyes are open or closed and often I can't tell. Thankfully during the day or when I'm in a well lit room I can see the patterns but they look more like a heat haze and as long as I keep my eyes focused only my peripheral vision moves but I still feel the movements of the patterns as movements of energy through my body and only in the last ten years have I really managed to be able to cope with it. Until I discovered diazepam in my 20s when I was sitting in a room with other people watching tv I suffered intense anxiety, I held my focus on the tv while everything around my point of vision moved leaving me feeling stuck to the seat as the movements of the patterns moved through my body. It has also affected every drug I have taken since, when I used to smoke cannabis I would see 3d spider's web type patterns that would seem to go on into infinity, as if looking at a wall is looking into a cinema screen. Around a year after taking the salvia and I was still wondering if it would ever go away was the first time I lost my fear of chemicals and decided to try ecstasy for my 17th birthday because of its connection to the rave music that is by far the most important thing in my life and the sound changed my life long before I knew what drugs were. Anyway, on the comedown I could see fantastic moving spiderweb patterns over the top of everything I could see as real, I asked everyone I was taking it with if they were tripping and they couldn't understand why I was. After that I kept it to myself, tried to just get on with life and force through the anxiety. 2 years later I met my first girlfriend and I told her about salvia, I had been keeping up to date with the salvia research centre online as they hadn't yet found what receptor it was binding to to cause it's effects, my girlfriend was studying neuroscience so when they found out that salvinorin A binds to the kappa opioid receptor this was really interesting to her, also it is the only psychoactive substance which doesn't contain nitrogen in its structure so she wrote a paper on it for one of her assignments only for it to be laughed as as the day before it was on a morning talk show as a new legal high and everyone thought she got her idea from that. In the last few years I have spent short spells in prison and having the ability to self medicate taken away from me has been absolute torture. I am doing my best to turn my life around so I never have to go through experiences like that again and without benzodiazepines I would be unable to fuction as a normal person and my anxiety would be so bad I would never leave the house or be able to interact with people without being uneasy shaky and paranoid. This month is my 20 year anniversary and after the first 10 years I began to break down, now I have a full time support worker and when the covoid lock down is eased I will moving into supported housing so that my worker can come to appointments etc with me and make sure I get the benefits I'm entitled to as they have been back logged because of the corona virus. Even with access to benzodiazepines because I can only take enough to calm my anxiety I never get any rest during the day and have to wait till night to take enough to relax and sleep. I'm prison I started speaking to clinical psychologists for the first time and am waiting to continue treatment and hopefully be given an official diagnosis. Thanks for taking the time to read my introduction. I hope this site will help me and allow me to help others. Murray Anderson

So, quick for introduction to my background in regards of HPPD, I have done a whole bunch of drugs before and I already had HPPD in a major developement and tried to manage it with certain forms of therapy and by giving it aome conciouss time... my constant symptoms when it was the best were tracers and that a part of my concioussess is in the spirit world which is very fine with me. I pretty much had trust in DMT and Salvia (I don´t know why I trusted Salvia I only tryed it a few times before and one time it even scared me, with that I have to mention that I am used to trip hard and that it is hard to scare me in this sense ) To the topic... about 26h ago I tripped hard on salvia while I was on Paracetamol ( stupidity is big in this one because I forgot that I was taking Paracetamol because I took it as medication for my cold, knowing that Paracetamol has some sort of not fully researched effect on opioid eceptor and the fact that Salvinorin-a bind onto kappa-opioid receptors I propably wouldn´t have done the salvia) After the trip I instantly wrote down my experience and while writing it down I started this feeling in my body arise, it was a combination between the HPPD I got from a 2cb x MDMA x Methamphetamine x Cannabis and the HPPD I got from a painfull experience with 5HTP and LSD just mixed into this salvia dissociation and trip I slept hours longer than I usually do and woke up very dissociated The dissociation is my main problem with this case of HPPD because it is not only like depersonalization/dissociation-syndrome it has it´s very own vibe ( like every HPPD) ... I just never had HPPD from a dissociative psychedelic I guess^^ other symptoms include: very strong enhancement of colours ( even stronger that it was with the LSD HPPD) ,constant contact/concioussness with/about these imagined/normally unperceived entities that arise when tripping hard on salvia, also I don´t have small visuals in my visual field like specific tracers for this HPPD or swirls or anything but my whole vision is moving as one most of the time when it is weaker ( as if I knew the world was spinning) when it gets worse I can´t see sharply and more complex geometric patterns are in my whole visual field. I hope someone here can help me or that I can at least find some kind souls to share a path together much love and light Ari

Hey guys. First and foremost; I wish I could put this all coherently in an elaborate article like I did with Coluracetam, however my current state does not allow for that, so forgive me if this all seems a bit vague or wishy-washy. This is a substance I've been wanting to try for months now. Basically what it is, is an orally active selective long and fast acting (~2 weeks) potent kappa opioid receptor (KOR) antagonist. Say that three times fast. The KOR is implicated in many things. Salvia Divinorum (more specifically, its active agent Salvinorin A), which I'm sure most of us are acquainted with, is a KOR agonist. So is Ketamine (see here a study with both aforementioned and JDTic). These both (as well as all KOR agonists) known to induce a state of dissociation, depersonalization, derealization, anxiety, cognitive impairment, as well as hallucinations/visual distortions, and perhaps some others nuisances I'm forgetting. Dynorphin is the endogenous KOR agonist, which appears to increase in levels under circumstances of stress and depression (see wiki), and also blocks glutamate release. Glutamate is also implicated in DP/DR as recently discussed, moreover it's the precursor to GABA, hence hypoglutamatergia is no fun. Furthermore, trying to agonize NMDA receptors for instance, would be kind of like mopping the floor with the faucet running. Though, as a side note, NRX-1074 (GLYX-13 derivative) would be really cool to try. Ok well.. I don't seem to be good at tying up the loose ends here, but in any case it seems to me to have a high chance of abolishing dissociative symptoms. Oh yes, Naloxone and Naltrexone have been used to treat DP, the former of which completely abolished it in several individuals, however Naloxone is unsustainable. JDTic seems to be relatively safe.. some concerns about 2/14 individuals having a transient heart arrhythmia or something benign like that, which is why they halted studies (protocol I guess). I'll try to add more later, but if you've any questions, please ask. This stuff is not available yet. I know many of you, like myself, are very willing to experiment if it's worth a shot, and this one most certainly is. There's not a group buy yet, but currently there are already 16 people interested in doing one. If you want to be a part of the group buy, and for far more elaborate discussion (and a lot of interesting articles), check out the Longecity thread. Also, for the only user review in the world, check out jdtic.com (bear in mind, this person did not suffer from any dissociative issues).

I get static pretty bad and the best way I can describe it is being somewhere between what I see and my thoughts. Along with static I have been seeing trippy stuff in this same plane of consciousness. Its like hallucinations that seem to fall short of reaching into my vision. Its like little pixels in my static are arranged into pictures that I can see overlapping my normal eyesight. I also feel like afterimages fit in this same place. I kind of think it is intertwined with my DP/DR, Its like I get so far dissociated from myself. These thoughts and visions are so powerful and out of my control that it can be pretty scary and overwhelming at times, but it really makes me wonder about the insane potential of the human brain.