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  1. Anyone have any experiences with Naltrexone? Or Naloxone, but I believe the latter is only available intravenously, hence I doubt anyone has tried this for the long-term. If you do have any experience with either of these, how did it help? Apparently Naloxone is pretty ace for DP, but of course comes with practical difficulties. An open trial of naltrexone in the treatment of depersonalization disorder. Effect of Naloxone therapy on depersonalization: a pilot study. Also Suboxone has been reported to help with DP/DR, but I haven't looked into that. What I'm interested in is "Amentoflavone", found in SJW and Ginkgo Biloba, which is an antagonist at the Kappa and Delta sites (not sure about the latter). No; this is not a hippie agenda, it's merely because Naltrexone, Naloxone, and Suboxone are particularly hard to get prescribed, thus Amentoflavone would be the easiest way to go. Anyway, you also might want to have a read through this post about Suboxone virtually curing DP. Though pure Amentoflavone is really expensive and hard to get, I'd thought that perhaps combining high-quality extracts of both SJW and Ginkgo Biloba may have a chance at helping.. Thinking about trying this out myself. I haven't ever tried SJW, so I thought it could be an interesting idea. As for Ginkgo; I've tried your average supermarket brand without any noticeable effects. Turns out that quality and brand really does matter, so it's worth giving another shot. Altogether that would be +/-$40 for a 20 day trial of both with the products I'm considering, so not ridiculously expensive. Input anyone?
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