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Found 7 results

  1. I want to offer an idea ... based on the theory of the death of GABA neurons, you can do the following: using Positron emission tomography using a radioligand, highlight GABA neurons by glutamate dercarboxylase (the enzyme that makes GABA) and compare this with the brain of a person healthy from hallucinations . it will be possible to see where and how many gaba neurons died
  2. Has anyone used this supplement? I know gaba plays a big role in hppd and i havent seen many trials on this supplement. Its only $10 so if no one has tried it, i will gladly guinea pig. So, please let me know! https://www.amazon.ca/gp/aw/d/B0013OVZAG/ref=pd_aw_sim_121_2?ie=UTF8&psc=1&refRID=2VHBYAHDRPDTKMXFFKFJ&dpPl=1&dpID=41gIOd1BtwL
  3. >Visits the doctors about HPPD, doctor doesn't know anything about HPPD >Tells doctor about persisting drug-induced hallucinations and panic attacks, gets referred to a drug and alcohol service >Makes it clear that there is no history of addiction or continued use, gets referred to psychiatrists >Open to suggestion, trying not to be classed as a drug-seeker, I accept the anti-psychotic prescription Seroquel >Takes Seroquel, makes HPPD worse, notifies doctors of this >Is offered SSRI anti-depressants for panic attacks, rejected them >Prescribed antipsychotic Olanzepine (Zyprexa), which doesn't do anything for HPPD, and Diazepam (Valium) for panic attacks, which also does nothing >Moved to a mental health facility so that doctors can sort medication out >Psychiatrists conclude that panic disorder can fix itself and that the HPPD visuals are psychotic hallucinations >Prescribes Aripiprazole (Abilify), and took away the Diazepam, which made HPPD worse, and induced anxiety and hypertension (high blood pressure) Psychiatrists insist that benzo's are unsafe and should only be used short term due to risk of addiction, despite no history of addiction and the thousands of milligrams worth of any benzodiazepine it would take to actually be fatal. Big fuck you to every single doctor out there who hasn't done their research and has treated every HPPD patient like this. I have already explained to them that the most effective treatment for HPPD include anti-convulsants, but they do not listen. Instead they want to chuck as many anti-psychotics and anti-depressants at me as possible, hoping that I will come across one that will eventually kill me. These doctors are not here to help, they are here to kill and deny effective treatment. Even if addiction were a problem (which is not if you do not abuse medicaiton), I'd rather be addicted to a drug than have HPPD for the rest of my life. Now I will proceed to seek medication illegally because this medical system has failed me.
  4. So I'm trying to do some homework on neurotransmitters to get a better understanding of what supplements and medications may benefit me most. I know my symptoms are always better in the morning and worse at night, that I don't respond well to stimulants (even medical ones prescribed by doctors), that I've had anxiety for years and my adrenals are likely fatigued, and that I do respond well to calming agents, as is the case with most people here. I do think one of my main problems is lack of dopamine, but I also know other neurotransmitters play a huge role in HPPD as well. So I guess I was just wondering what the consensus is on all this. I hear GABA thrown around a lot, but I have no idea how GABA works. Is more GABA better or less? And what about serotonin? Any responses are much appreciated. I've tried rummaging through the boards to read up about this stuff but there doesn't seem to be any single particular thread that summarizes all this briefly so perhaps someone could enlighten me. Not looking for anything too extensive, just a quick recap. Thanks.
  5. Hi everyone, Thanks for your time to anyone who is reading this. I have aways been a "sensory sensitive" person (i.e. only kid on a youth soccer team to have to wear sunglass sports goggles). I took LSD (one time only) during the summer after I graduated from college in 2006. Upon waking up the next morning (after little sleep lol) and getting my day started, it was overwhelmingly evident that something in my brain had changed. I have for the 8 years since then been dealing with a variety of extremely bothersome, what I would describe as, visual sensory overload issues. My brain is now agitated and overwhelmed by all sorts of visual stimuli, most notably unnatural lighting that I encounter in the evening (i.e. all forms of indoor lighting, car headlights, porchlights etc). Also, as crazy as it may sound, my brain is often extremely agitated and distracted by shadows that are created by such lights...things that my brain would have formerly subconsciously filtered out. For instance, an overhead fan with a light behind it will drive me absolutely crazy. I also have issues during daytime hours, though not as intensely, as I am also now more sensitive to brightness from the sun (as well as daytime shadows). When I am in the throes of my "symptoms", my experience ranges from mild agitation to literally feeling like my brain is on fire and in desperate need of someone popping my skull open to dump ice water onto it. This latter feeling generally arises from prolonged exposure, for instance a situation where I cannot just go take a shower to calm my brain down or lie down in a dark room for a while. I don't know if the condition I have is precisely HPPD, as I do not experience visual snow, halos, trailers, or any of the other "common symptoms" I have seen listed under diagnosis criteria for HPPD. However, I keep coming back to this forum and other websites related to HPPD because I have had a persisting sensory condition that was (however predisposed I may have been) either caused or multiplied a hundred times by taking a psychedelic drug. To wrap up with a few other details: I have suffered from Depersonalization Disorder since my senior year of high school (that I am certain was triggered or at least exacerbated by marijuana use). I have not taken any psychedelic drugs since my LSD experience, and have not smoked pot in about 7 years as it makes all of my symptoms much worse. I mostly try to sleep and exercise consistently to help me battle my problems. I have been to several people for help. A neurologist told me frankly that he understood in theory what I was saying, but had no idea what to do. I was later prescribed Xanax by a psychiatrist. It has helped me quite a bit and I generally take it at night time when my symptoms hit at their worst. I do hope to get off of it someday soon because of the zombie-ish feeling it can create. But for now, I much prefer it to the suffering I endure without it. I have been disciplined and have not upped my Xanax dosage during the 2 1/2 years I have been taking it. I believe that the condition I deal with might line up more closely with some of the sensory overload issues faced by MS or Autistic patients. It might very well be that certain receptors were overstimulated during my LSD experience and now my GABA production has been permanently affected. This would explain why taking a Benzo, like Xanax, temporarily makes me feel better. Drinking alcohol, though I don't often engage in it, has a slightly similar calming effect. If anyone has any thoughts, I would greatly appreciate hearing them. I am quite desperate, to be frank, and am open to all suggestions. N-Met is a product I have seen marketed for sensory overload sufferers, as well as GABA Calm. Keppra intrigues me as well because of it's work on GABA receptors, though I am a bit nervous about trying an anti-convulsant. I have also considered meeting with an Occupational Therapist, or a hypnotist. Thanks everyone! DJ
  6. I believe there are others on this forum suffering from bipolar disorder also... I am wondering if any of you have noticed changes in your hppd symptoms during depressive and manic episodes? I was on Lamictal for about a year and it helped with both, but at the beginning of this summer I quitted cold after forgetting to take it for several days and thinking I was still feeling ok. The hppd symptoms came back after a while, but they didn't bother me much so I somehow delayed taking my meds until today.... I guess lately I've been going through my first hypomanic episode since I got hppd, and during this time it seems like my hppd symptoms got better. Which scares me, because I've been impulsively doing drugs again... (When I'm depressed, I don't do any drugs because even before hppd, everything I did led to panic attacks) I actually feel quite ok, It feels nice to be able to do drugs and have fun again... I sometimes think that maybe it's just me being paranoid, maybe I'm actually cured... But I recognized this pattern a few days ago, after my second lsd trip this month. The last time I was feeling and acting this way, I ended up having HPPD. I'm scared of what could happen after this illusion of feeling good is gone. I started taking Lamictal again today, I hope that it will help the way it did before... I would like to hear about your experiences... Also, I know that same neurotransmitters are affecting both conditions in some way, but I don't understand the mechanisms that much and would like to learn about it more. Any reading suggestions?
  7. File Name: GABA-A receptor subtype selectivity underlying selective anxiolytic effect of baicalin File Submitter: StateOfRegret File Submitted: 05 Mar 2014 File Category: Publications GABA-A receptor subtype selectivity underlying selective anxiolytic effect of baicalin. Click here to download this file
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