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  1. For those looking for new solutions, a bit can be learned from old solutions ... Quinine has been in use since the 1800's. Its main purpose is to treat malaria. However, it used to be used as a general tonic. Today it is still readily available in tonic water, as those of you who love G&Ts (Gin and Tonic) might know. It is derived from the bark of Cinchona trees/bushes. Like most meds, they don't know how it works for malaria. It relaxes smooth muscle like an anticholergenic. It does affect dopamine activity. It seems to alter the ANS as well as the CNS (See posts regarding Ca, Mg, and K such as #39 http://hppdonline.com/index.php?/topic/1959-spitting-out-yet-another-theory-magnesium/) It isn't a med to take high amounts unless you have malaria (~2g per day). See http://www.aspenpharma.com.au/product_info/pi/PI_Quinate.pdf However, as stated above, it is in genuine tonic water with amounts limited to about 80mg per quart. And they haven't issued any warning about too many G&Ts - Twenty Five quarts a day would treat malaria . I've only worked with 75mg at a time ... and then only a few times (will let you know if anything significant occurs, good or bad). It reduces DR (defined in this case as the feeling of disconnection, as if there is a transparent barrier between the world and self) and is relaxing - all this without the Gin. Can be quite sedative. Feels like a cross between Keppra and Sinemet. Hope this is helpful. Have fun and enjoy your G&T! Miscellaneous bedtime reading: http://www.ncbi.nlm.nih.gov/pubmed/2759182 http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.1992.tb10993.x/abstract http://www.ncbi.nlm.nih.gov/pubmed/1357098 http://www.ncbi.nlm.nih.gov/pubmed/11797417 http://www.progressivehealth.com/rls-quinine.htm http://www.nourishing-the-soul.com/2010/06/mood-food-connection/ http://www.sciencedirect.com/science/article/pii/0306362377900118 http://link.springer.com/article/10.1007%2FBF00688932
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